Protein Alignment Mmp2 and mmp20b

DIOPT Version :9

• Sequence 1: NP_995788.1
• Gene: Mmp2 / 35997
• FlyBaseID: FBgn0033438
• Length: 758
• Species: Drosophila melanogaster
• Sequence 2: XP_009290029.1
• Gene: mmp20b / 100537445
• ZFINID: ZDB-GENE-100603-3
• Length: 490
• Species: Danio rerio
• Alignment Length: 728
• Identity: 168/728 - (23%)
• Similarity: 258/728 - (35%)
• Gaps: 266/728 - (36%)

  Fly     6 VLATLLALFAQSMCIQELSLP-PEGS----HSTAATRSKKAKTAISEDIMYNYLMQFDYLPKSDL 65
            ||..|:..|  .:..|..||| |.|.    |.|     |.|:..:|  :...||.|| |..::|.
Zfish     3 VLLCLVCAF--DLFGQHYSLPLPLGDDGMVHPT-----KPAQNDLS--LATKYLQQF-YSFQADS 57

  Fly    66 ETGALRTEDQLKEAIRSLQSFGNITVTGEIDSATARLIQKPRCGVGDRRSADSFSPDNLYHEIGS 130
            .....|:.......::::|.|..:..||.:::.|..:::.|||||.|   .:.:|     |.
Zfish    58 AGRKRRSRPSFSSKLKNMQGFFGLNGTGTLNADTLAVMRTPRCGVSD---VEDYS-----HR--- 111

  Fly   131 NVRVRRFALQGPKWSRTDLTWSMVNRSMPD--ASKVERMVQTALDVWANHSKLTFREVYSDQADI 193
                     :|.:|.:..:|:. |.|...|  .:.|:.::.:||||||..|.|||...||.||||
Zfish   112 ---------RGNRWKKNIITYG-VGRYTNDLPVNAVDDLISSALDVWAKASPLTFLRSYSHQADI 166

  Fly   194 QILFARRAHGDGYKFDGPGQVLAHAFYPGEGRGGDAHFDADETWNFDGESDDSHGTNFLNVALHE 258
            .:.|..:.|||.:.||||...|||||.||||.|||.|||..|.|     :...:|.|...||.||
Zfish   167 MVEFVGKEHGDFFPFDGPDGTLAHAFGPGEGIGGDVHFDEAEVW-----TAGYNGFNLYVVAAHE 226

  Fly   259 LGHSLGLAHSAIPDAVMFPWYQNNEVAGNLPDDDRYGIQQLYGTKEKTWGPYKPQTTTTTTTTTT 323
            .||:|||.||.:|::||:|.|:..:....|..:|...|..|||.::|.  || |.:.
Zfish   227 FGHALGLKHSQLPESVMYPTYKRRKTHNLLSSEDIININTLYGPRDKR--PY-PSSR-------- 280

  Fly   324 MRAMIYRADKPAYWPWNNPSNNPNNDRNRARERQEEERRRQEKERRRQEEERRHQEEERRRQVEE 388
                         :.|:|||
Zfish   281 -------------FSWSNPS--------------------------------------------- 287

  Fly   389 RQRQEEERWRQEQERQEEENRRRKIEHKSQWERNPSKERNRPRERQEMERRRQEQERQEQERQEQ 453
                                                                             
Zfish   288 ----------------------------------------------------------------- 287

  Fly   454 EDRRRERERDRQLEWERRNRNGAREPVTPTANTTPRPTNKPYPTVHRQHHHHNKPRKPKPDSCMT 518
                                             ||..:...:|...:             |:|..
Zfish   288 ---------------------------------TPWYSGSYFPVSFK-------------DTCNP 306

  Fly   519 Y--YDAISIIRGELFIFRGPYLW------RIGTSGLYNGYPTEIRRHWSALPENLTKVDAVYENK 575
            :  :||::.:...:|.||..|:|      :....|..:.:..:|..|          :||.|...
Zfish   307 HLKFDAVTTVGDAIFFFRDNYMWIKHNDQKDIKEGPISNFMPKIDCH----------IDAAYWVP 361

  Fly   576 QRQIVFFIGREYYVFNSVML-------APGFPKPLASLGLPPTLTHIDASFVWGHNNRTYMT--- 630
            ||...       |:||....       ..|..|.::|||.|..:..:||:.   |.::|..|
Zfish   362 QRSTA-------YLFNGTTFWTVKGSQVKGRAKNISSLGFPSWVQQVDAAV---HIHKTVHTLFF 416

  Fly   631 SGTLYWRIDDYTGQVELDYPRDMS-IWSGVGYNIDAAFQYLDGKTYFFKNLGYWEFNDDRMKVAH 694
            :...|||.:::...:....||::| .:..:...|.||. |.||..:||.....::: |.:.|...
Zfish   417 TQHQYWRYNEHNKNMTDSIPRNISDDFPEISGPISAAI-YKDGYLHFFIGSDVYKY-DIKQKEII 479

  Fly   695 ARAKLSARRWMQC 707
            ...|.::  |:.|
Zfish   480 GTDKTTS--WLGC 490

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mmp2	NP_995788.1	Peptidase_M10	143..301	CDD:278824	69/159 (43%)
		ZnMc_MMP	143..301	CDD:239805	69/159 (43%)
		HX	513..707	CDD:238046	49/212 (23%)
mmp20b	XP_009290029.1	PG_binding_1	45..95	CDD:279773	12/50 (24%)
		Peptidase_M10	115..269	CDD:278824	69/159 (43%)
		ZnMc_MMP	115..269	CDD:239805	69/159 (43%)
		HX	304..490	CDD:238046	48/209 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1565
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1075463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10201
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X44
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.920