Protein Alignment Mmp2 and mmp19

DIOPT Version :9

• Sequence 1: NP_995788.1
• Gene: Mmp2 / 35997
• FlyBaseID: FBgn0033438
• Length: 758
• Species: Drosophila melanogaster
• Sequence 2: XP_021335657.1
• Gene: mmp19 / 100536874
• ZFINID: ZDB-GENE-100308-3
• Length: 451
• Species: Danio rerio
• Alignment Length: 672
• Identity: 167/672 - (24%)
• Similarity: 247/672 - (36%)
• Gaps: 236/672 - (35%)

  Fly    50 MYN-YLMQFDYLPKSDLETGALR--TEDQLKEAIRSLQSFGNITVTGEIDSATARLIQKPRCGVG 111
            ||: ||.:|.|| .:.|...|.|  :|..:|.|:...|....:.|||.:|.||...:::|||||.
Zfish     1 MYSTYLRRFGYL-DTPLNPEAQRDSSEWDMKVALSLFQRVSGLPVTGNLDRATVFKMREPRCGVE 64

  Fly   112 DRRSADSFSPDNLYHEIGSNVRVRRFALQGPKWSRTDLTWSMVNRSMPDASK--VERMVQTALDV 174
            |..:..||             :.|||..    |.:.:||:.:.|.: ||..|  .:..::||...
Zfish    65 DPFNQKSF-------------KYRRFGY----WRKKNLTYRIYNYT-PDMGKSATQTAIRTAFKY 111

  Fly   175 WANHSKLTFREVYSDQADIQILFARRAHGDG--YKFDGPGQVLAHAFYPGEGRGGDAHFDADETW 237
            |::.:.|:|.|::...|||:|.|.:|   ||  ..|||||.|||||..|   ..|..|||.||.|
Zfish   112 WSDVTPLSFTEIHFGTADIRISFHKR---DGCPSPFDGPGHVLAHAEAP---PSGIVHFDEDEFW 170

  Fly   238 NFDGESDDSHGTNFLNVALHELGHSLGLAHSAIPDAVMFPWYQNNEVAGNLPDDDRYGIQQLYGT 302
            . :|:   .:|:|...||.||:||:|||.||....|:|...|...:|...|..||..|||.:||.
Zfish   171 T-EGK---YYGSNLRIVAAHEIGHALGLGHSQYSSALMAAHYTGYQVNFRLHIDDIRGIQAIYGK 231

  Fly   303 KEKTWGPYKPQTTTTTTTTTTMRAMIYRADKPAYWPWNNPSNNPNNDRNRARERQEEERRRQEKE 367
            :           .::|||...    ||
Zfish   232 R-----------VSSTTTADD----IY-------------------------------------- 243

  Fly   368 RRRQEEERRHQEEERRRQVEERQRQEEERWRQEQERQEEENRRRKIEHKSQWERNPSKERNRPRE 432
                                                                             
Zfish   244 ----------------------------------------------------------------- 243

  Fly   433 RQEMERRRQEQERQEQERQEQEDRRRERERDRQLEWERRNRNGAREPVTPTANTTPRPTNKPYPT 497
                                                          .||             |||
Zfish   244 ----------------------------------------------DVT-------------YPT 249

  Fly   498 VHRQHHHHNKPRKPKPDSCMTYYDAISIIR-----GELFIFRGPYLWRIGTSGLYNGYPTEIRRH 557
            :....     ||....|.|....|||.::.     .:.:.|.|.|:|.:..:|  :..|.:|...
Zfish   250 MMAPF-----PRGDVLDPCNAKLDAIMLVLVSGPWRKTYAFSGDYVWTVTDTG--HNSPVKINLL 307

  Fly   558 WSALPENLTKVDAVYENKQRQIVFFIGREYYVFNSVMLAPGFPKPLASLGLPPTLTHIDASFVWG 622
            |..||.||..  |||.::..:..||.|.:.:.:.:..|...:||||..:.     .:|||:....
Zfish   308 WKGLPGNLNA--AVYSSRTNKTYFFKGEKVWRYTNYRLDYRYPKPLKRIP-----ANIDAALYHE 365

  Fly   623 HNNRTYMTSGTLYWRIDDYTGQVELDYPRDMS-IWSGVGYNIDAAFQYLDGKTYFFKNLGYWEFN 686
            .|.:.:...|:.||:.|:........||:.:| :::|:..|.||:|.:.:||.||||...||..:
Zfish   366 KNKKIFFFKGSGYWQWDEMVYNDLSIYPKPISRLFTGIPSNPDASFTWTNGKMYFFKGDKYWRVS 430

  Fly   687 DDRMKVAHARAKLSAR-RWMQC 707
            :  .....:...||.| |||:|
Zfish   431 E--QFTVDSGYPLSKRVRWMRC 450

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mmp2	NP_995788.1	Peptidase_M10	143..301	CDD:278824	63/161 (39%)
		ZnMc_MMP	143..301	CDD:239805	63/161 (39%)
		HX	513..707	CDD:238046	58/200 (29%)
mmp19	XP_021335657.1	PG_binding_1	4..53	CDD:307564	17/49 (35%)
		ZnMc_MMP	80..230	CDD:239805	63/160 (39%)
		HX	261..450	CDD:238046	58/199 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1565
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1075463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10201
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X44
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.920