Protein Alignment Mmp2 and mmp8

DIOPT Version :9

• Sequence 1: NP_995788.1
• Gene: Mmp2 / 35997
• FlyBaseID: FBgn0033438
• Length: 758
• Species: Drosophila melanogaster
• Sequence 2: XP_002944454.2
• Gene: mmp8 / 100494588
• XenbaseID: XB-GENE-952402
• Length: 455
• Species: Xenopus tropicalis
• Alignment Length: 667
• Identity: 167/667 - (25%)
• Similarity: 244/667 - (36%)
• Gaps: 249/667 - (37%)

  Fly    51 YNYLMQFDYLPKSDLETGALRTEDQLKEAIRSLQSFGNITVTGEIDSATARLIQKPRCGVGDRRS 115
            :|.....:||.|.....|...:...|.:.|:.:|:|..:.||..::..|..::::|||||.|...
 Frog    28 HNEAFAKEYLKKFYRFEGEGTSRSALLDKIQKMQNFFGLEVTARLNEETIDVMKQPRCGVPDIAR 92

  Fly   116 ADSFSPDNLYHEIGSNVRVRRFALQGPKWSRTDLTWSMVNRSMPDASK--VERMVQTALDVWANH 178
            ..:||        |:.|           |.:.|||:.::|.: ||.::  |:|.::.|..||::.
 Frog    93 FSTFS--------GNAV-----------WKKKDLTYRILNYT-PDMTRNDVDRAIEKAFKVWSDV 137

  Fly   179 SKLTFREVYSDQADIQILFARRAHGDGYKFDGPGQVLAHAFYPGEGRGGDAHFDADETWNFDGES 243
            ..|||..:|...:||::|||.|.|.|...||||..:|||||.||:..|||.|||.||.|     :
 Frog   138 VPLTFTRIYDRVSDIEMLFAYRDHKDSLPFDGPSGILAHAFAPGDNIGGDVHFDEDEKW-----T 197

  Fly   244 DDSHGTNFLNVALHELGHSLGLAHSAIPDAVMFPWYQN-NEVAGNLPDDDRYGIQQLYGTKEKTW 307
            ..|.|||...||.|||||||||.||..|:|:|:|.|.. |.....||.||..||..||||||
 Frog   198 SGSAGTNLFLVAAHELGHSLGLDHSNDPNALMYPTYHYINPNTFQLPQDDINGIHSLYGTKE--- 259

  Fly   308 GPYKPQTTTTTTTTTTMRAMIYRADKPAYWPWNNPSNNPNNDRNRARERQEEERRRQEKERRRQE 372
                                                                             
 Frog   260 ----------------------------------------------------------------- 259

  Fly   373 EERRHQEEERRRQVEERQRQEEERWRQEQERQEEENRRRKIEHKSQWERNPSKERNRPRERQEME 437
                                                                             
 Frog   260 ----------------------------------------------------------------- 259

  Fly   438 RRRQEQERQEQERQEQEDRRRERERDRQLEWERRNRNGAREPVTPTANTTPRPTNKPYPTVHRQH 502
                                                    .|:.|..|...:.:
 Frog   260 ----------------------------------------NPIIPIINCQEQIS----------- 273

  Fly   503 HHHNKPRKPKPDSCMTYYDAISIIRGELFIFRGPYLWRIGTSGLYNGYPTEIRRH-----WSALP 562
                             :||::.:||::..|:....|| .|:|     .:||.:|     |.:||
 Frog   274 -----------------FDAVTTLRGDILFFKNRSFWR-KTAG-----KSEIEQHEISSFWPSLP 315

  Fly   563 ENLTKVDAVYEN-KQRQIVFFIGREYYVFNSVMLAPGFPKPLASLGLPPTLTHIDASFVWGHNNR 626
            .:.   ||.||| |:.|::.|.|.:|:|.....:..||||.:..||.|.|:|.|||:.......|
 Frog   316 ADF---DAAYENQKKDQVLLFKGTKYWVLRGYTIQEGFPKNIYELGFPLTVTQIDAAVHDDETGR 377

  Fly   627 TYMTSGTLYWRIDDYTGQVELDYPRDMSI-WSGVGYNIDAAFQYLDGKTYFFKNLGYWEFNDDRM 690
            ||......||..::.|.|::.:.|:.:|. :.|||..::|||: .:|..|.|.....:||:....
 Frog   378 TYFFINDRYWSYNEETSQMDKESPQRISKGFPGVGNKVEAAFR-SNGMLYLFSGNQQYEFSTTNR 441

  Fly   691 KVAHARAKLSARRWMQC 707
            ||...   |....|:.|
 Frog   442 KVTRL---LKYTSWLNC 455

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mmp2	NP_995788.1	Peptidase_M10	143..301	CDD:278824	74/160 (46%)
		ZnMc_MMP	143..301	CDD:239805	74/160 (46%)
		HX	513..707	CDD:238046	62/200 (31%)
mmp8	XP_002944454.2	PG_binding_1	33..80	CDD:279773	11/46 (24%)
		Peptidase_M10	102..256	CDD:278824	74/159 (47%)
		ZnMc_MMP	102..256	CDD:239805	74/159 (47%)
		HX	271..455	CDD:238046	62/224 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	145	1.000	Domainoid score	I4538
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1075463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10201
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X44
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.110