Protein Alignment Mmp2 and LOC100493912

DIOPT Version :10

• Sequence 1: NP_995788.1
• Gene: Mmp2 / 35997
• FlyBaseID: FBgn0033438
• Length: 758
• Species: Drosophila melanogaster
• Sequence 2: XP_031750963.1
• Gene: LOC100493912 / 100493912
• XenbaseID: XB-GENE-29081943
• Length: 861
• Species: Xenopus tropicalis
• Alignment Length: 700
• Identity: 138/700 - (19%)
• Similarity: 197/700 - (28%)
• Gaps: 326/700 - (46%)

  Fly    57 FDYLPKSDLETGALRTEDQLKEAIRSLQSFGNITVTGEIDSATARLIQKPRCGVGDRR------- 114
            ||.:..:|||   |....:...|:|..|....:.|||.:|:||...:..|||||.|.|
 Frog   339 FDSVSPTDLE---LTLNPRFNGALRRFQEANKLEVTGRLDAATIMAMNVPRCGVPDHRVPEGVGA 400

  Fly   115 -------------SADSFSPD---NLYHEIGSNVRVRRFALQGP--------------------K 143
                         |.:|.|.:   :.|.|.....:.|..||..|                    .
 Frog   401 QPEDPEENGSTTLSINSESAEENRDTYEESAEEYQERGQALGLPAKRQVRRKRSQLLKAGAKRAA 465

  Fly   144 WSRTDLTWSMVNR--SMPDASKVER-MVQTALDVWANHSKLTFREVYSDQA---DIQILFARRAH 202
            :|:..|.|.::..  |:..:.:.:| :::.|..:|:....|.|:|..|..|   ||::.|..|.|
 Frog   466 FSKLTLKWRLLGEGYSVWLSKEQQRYILRLAFRMWSEVVPLNFQEDLSSPAQLIDIKLGFGTRRH 530

  Fly   203 -GDGYKFDGPGQVLAHAFYPGEGRGGDAHFDADETWNFDGESDDSHGTNFLNVALHELGHSLGLA 266
             |....||..|:..|||:     :.||.||:.||.:   ...:..||.:.|.||:||:||.|||:
 Frog   531 LGCSQLFDDMGREFAHAW-----QLGDIHFNDDEHF---VPPNSEHGISLLKVAVHEIGHVLGLS 587

  Fly   267 HSAIPDAVMFPWYQNNEVAGNLPDDDRYGIQQLYGTKEKTWGPYKPQTTTTTTTTTTMRAMIYRA 331
            |.....:||.|.|........|...||..||::||   |..|.:.
 Frog   588 HMNHLGSVMQPNYIPANGKMELGWTDRRAIQKIYG---KCSGRFS-------------------- 629

  Fly   332 DKPAYWPWNNPSNNPNNDRNRARERQEEERRRQEKERRRQEEERRHQEEERRRQVEERQRQEEER 396
               ..:.|                                    .|||.:
 Frog   630 ---TVFDW------------------------------------VHQEPD--------------- 640

  Fly   397 WRQEQERQEEENRRRKIEHKSQWERNPSKERNRPRERQEMERRRQEQERQEQERQEQEDRRRERE 461
                                                                             
 Frog   641 ----------------------------------------------------------------- 640

  Fly   462 RDRQLEWERRNRNGAREPVTPTANTTPRPTNKPYPTVHRQHHHHNKPRKPKPDSCMTYYDAISII 526
                                               .:..|..|:|           ||:
 Frog   641 -----------------------------------DLGHQVSHYN-----------TYF------ 653

  Fly   527 RGELFIFRGPYLWRIGTSG--LYNGYPTEIRRHWSALPENLTKVDAVYENKQRQIVFFIGREYYV 589
                  ||..:.||...|.  .:.|||.|::..|..:|.  ..:||
 Frog   654 ------FRRSWYWRYENSSNRTWYGYPQELKVGWEGIPH--ADIDA------------------- 691

  Fly   590 FNSVMLAPGFPKPLASLGLPPTLTHIDASFVWGHNNR-TYMTSGTLYWRIDDYT---------GQ 644
                                  ..|.     |..|.| |:...|.||||.||..         |.
 Frog   692 ----------------------FLHF-----WTRNKRFTFFFKGKLYWRYDDQNDRAYRQDPEGH 729

  Fly   645 VELDYPRDMSI-WSGVGYNIDAAF-QYLDGKTYFFKNLGYWEFNDDRMKV 692
            :   |||.:|. :.|:|..||..| ...|...|||.......|..:..||
 Frog   730 I---YPRLISEGFPGIGGPIDTVFYDQRDHNIYFFHGRNVTAFGVESQKV 776

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mmp2	NP_995788.1	PG_binding_1	52..103	CDD:460223	15/45 (33%)
		Peptidase_M10	143..301	CDD:425668	52/164 (32%)
		HX	513..707	CDD:238046	43/193 (22%)
LOC100493912	XP_031750963.1	Nnr1	<78..297	CDD:439832
		PG_binding_1	<358..382	CDD:460223	9/23 (39%)
		ZnMc_MMP	466..622	CDD:239805	52/163 (32%)
		HX	651..822	CDD:413329	43/188 (23%)