Protein Alignment Mmp2 and mmp21l

DIOPT Version :10

• Sequence 1: NP_995788.1
• Gene: Mmp2 / 35997
• FlyBaseID: FBgn0033438
• Length: 758
• Species: Drosophila melanogaster
• Sequence 2: XP_002939653.2
• Gene: mmp21l / 100492075
• XenbaseID: XB-GENE-29071363
• Length: 616
• Species: Xenopus tropicalis
• Alignment Length: 691
• Identity: 150/691 - (21%)
• Similarity: 217/691 - (31%)
• Gaps: 290/691 - (41%)

  Fly    78 EAIRSLQSFGNITVTGEIDSATARLIQKPRCGVGD------RRSA-----DSFSPDNLYHEIGSN 131
            ::::..|....:|.||.:||||...:.||||||.|      |::|     |:.|..:...:.|:.
 Frog   121 DSLKKFQDANGLTATGVLDSATKIAMNKPRCGVPDFKVASRRKNATLSFTDADSNSHNSSQAGAT 185

  Fly   132 VRVRRFAL--------------------QGPKWSRTDLTWSMVNR--SMPDASKVER-MVQTALD 173
            .|.:|..|                    ...::||..:.|.::..  ||....:.:| ::..|..
 Frog   186 QRRKRSFLSKMVEHYRQKREAKDTMGSSNSKRFSRNTVKWRLMGEGYSMQLTIQQQRAILALAFR 250

  Fly   174 VWANHSKLTF-REVYSDQADIQILFARRAH-GDGYKFDGPGQVLAHAFYPGEGRGGDAHFDADET 236
            :|:....|.| .::..|..||:|.|....| |....|||.||..|||:|.     ||.|||.||
 Frog   251 MWSEVVPLLFVEDLTGDDIDIRIGFGTGQHLGCSQAFDGVGQQFAHAWYL-----GDIHFDDDE- 309

  Fly   237 WNFDGESDDSHGTNFLNVALHELGHSLGLAHSAIPDAVMFPWYQNNEVAGNLPDDDRYGIQQLYG 301
             :|.|.|.: ||.:.|.||:||:||:|||:|.....:||.|.|...|....|..:||..:|:.||
 Frog   310 -HFVGPSSE-HGISLLKVAVHEIGHALGLSHINREGSVMQPNYIPQERHFELDWEDRKAVQEKYG 372

  Fly   302 T-------------KEKTWGPYKPQTTTTTTTTTTMRAMIYRADKPAYWPWNNPSNNPNNDRNRA 353
            .             ||:|     |:..|.....|      |......||.:.|.||
 Frog   373 ACDGSFSTVFDWIRKERT-----PRGETVYRFNT------YFFKTNWYWMYENKSN--------- 417

  Fly   354 RERQEEERRRQEKERRRQEEERRHQEEERRRQVEERQRQEEERWRQEQERQEEENRRRKIEHKSQ 418
                                                                             
 Frog   418 ----------------------------------------------------------------- 417

  Fly   419 WERNPSKERNRPRERQEMERRRQEQERQEQERQEQEDRRRERERDRQLEWERRNRNGAREPVTPT 483
                                                                |.|.|...|:...
 Frog   418 ----------------------------------------------------RTRFGDPLPIKGG 430

  Fly   484 ANTTPRPTNKPYPTVHRQHHHHNKPRKPKPDSCMTY-YDAISIIRGELFIFRGPYLWRIGTSGLY 547
            .|..|......|  ||                ..|: .||       .:.|:|..:||      |
 Frog   431 WNGIPDKDIDAY--VH----------------VWTWNIDA-------QYFFKGTQVWR------Y 464

  Fly   548 N--------------GYPTEIRRHWSALPENLTKVDAVYEN-KQRQIVFFIGREYYVF--NSVML 595
            :              .||..|...:..:|   :.|||.|.| |:|.|.||.|.....|  :....
 Frog   465 DPDKDRAFTEDWRKVKYPQPIADVFPGIP---SPVDAAYFNKKERFIYFFRGNNVTAFSVDKNQK 526

  Fly   596 APGFPKPLASLGLPPTLTHIDASFVWGHNNRTYMTSGTLYWRIDDYTGQVELDYPRDMSIWSGVG 660
            ...|||.:..: .||    :|.:                             |:||.
 Frog   527 VEKFPKSIIDV-FPP----VDPN-----------------------------DHPRG-------- 549

  Fly   661 YNIDAA-FQYLDGKTYFFKNLGYWEFNDDRMKVAHARAKLS 700
             ||||. |.|....|:|.|:..||:...|:.:..::...|:
 Frog   550 -NIDAVYFSYSYQTTFFIKDKYYWKMVIDQERQTNSSLPLN 589

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mmp2	NP_995788.1	PG_binding_1	52..103	CDD:460223	8/24 (33%)
		Peptidase_M10	143..301	CDD:425668	58/162 (36%)
		HX	513..707	CDD:238046	46/207 (22%)
mmp21l	XP_002939653.2	PG_binding_1	<123..146	CDD:460223	8/22 (36%)
		ZnMc_MMP	217..372	CDD:239805	58/162 (36%)
		HX	373..602	CDD:413329	67/431 (16%)