Protein Alignment Mmp2 and mmp20

DIOPT Version :10

• Sequence 1: NP_995788.1
• Gene: Mmp2 / 35997
• FlyBaseID: FBgn0033438
• Length: 758
• Species: Drosophila melanogaster
• Sequence 2: XP_012813779.1
• Gene: mmp20 / 100489409
• XenbaseID: XB-GENE-852914
• Length: 478
• Species: Xenopus tropicalis
• Alignment Length: 662
• Identity: 159/662 - (24%)
• Similarity: 236/662 - (35%)
• Gaps: 238/662 - (35%)

  Fly    58 DYLPKSDLETGALRTED------QLKEAIRSLQSFGNITVTGEIDSATARLIQKPRCGVGDRRSA 116
            :||.|...:.|.:|..:      .:...||.:|.|..:.|||::|.:|..::||||||:.|..:
 Frog    43 EYLDKYYSDRGTMRVAEMVADDVSMSRKIRKMQKFFGLQVTGKLDHSTLAVMQKPRCGMPDLAN- 106

  Fly   117 DSFSPDNLYHEIGSNVRVRRFALQGPKWSRTDLTWSMVN-RSMPDASKVERMVQTALDVWANHSK 180
                    ||.....          |||.|:.||:.:.. .|......|:|.|...|..|::.:.
 Frog   107 --------YHVFPGE----------PKWQRSSLTYRITKYTSSLSTQDVDRAVDLGLKAWSDAAP 153

  Fly   181 LTFREVYSDQADIQILFARRAHGDGYKFDGPGQVLAHAFYPGEGRGGDAHFDADETWNFDGESDD 245
            |.|.:....:|||.|.|....|||.|.||||...|||||.||||.|||.|||..|.|     :..
 Frog   154 LNFIKTTQGEADIMISFESGDHGDSYPFDGPRGTLAHAFAPGEGLGGDTHFDNAERW-----TTG 213

  Fly   246 SHGTNFLNVALHELGHSLGLAHSAIPDAVMFPWYQNNEVAG-NLPDDDRYGIQQLYGTKEKTWGP 309
            .:|.|...||.||.||:|||.||:.|.|:|:|.|:.....| .||.||..|||.|||||
 Frog   214 KNGFNLFTVAAHEFGHALGLGHSSDPSALMYPTYRYQHPIGFQLPTDDVKGIQALYGTK------ 272

  Fly   310 YKPQTTTTTTTTTTMRAMIYRADKPAYWPWNNPSNNPNNDRNRARERQEEERRRQEKERRRQEEE 374
                                                                             
 Frog   273 ----------------------------------------------------------------- 272

  Fly   375 RRHQEEERRRQVEERQRQEEERWRQEQERQEEENRRRKIEHKSQWERNPSKERNRPRERQEMERR 439
                                                                             
 Frog   273 ----------------------------------------------------------------- 272

  Fly   440 RQEQERQEQERQEQEDRRRERERDRQLEWERRNRNGAREPVTPTANTTPRPTNKPYPTVHRQHHH 504
                                             ..|..:|:.|     .:|.|
 Frog   273 ---------------------------------GIGKEKPMAP-----QQPAN------------ 287

  Fly   505 HNKPRKPKPDSC--MTYYDAISIIRGELFIFRGPYLWRIGTSGLYNGYPTEIRRHWSALPENLTK 567
                   |||.|  ...:||::::..||..|:....|| ..:.|.|..|:.|.   |:.|:.::.
 Frog   288 -------KPDQCDPNLSFDAVTVLGNELLFFKERSFWR-RQAPLTNIGPSPIA---SSFPQLMSN 341

  Fly   568 VDAVYE-NKQRQIVFFIGREYYVFNSVMLAPGFPKPLASLGLPPTLTHIDASFVWGHNNRTYMTS 631
            |||.|| .:|....||.|..|:....:.: .|.|:.:...|.|..:..|||:....::.:|....
 Frog   342 VDAAYEVAEQGTAYFFKGPHYWATRGLQM-QGHPRTIYDFGFPRHVQKIDAAVHLKNSRKTLFFV 405

  Fly   632 GTLYWRIDDYTGQVELDYPRDM-SIWSGVGYNIDAAFQYLDGKTYFFKNLGYWEFNDDRMKVAHA 695
            |..|:..|:...::|.|||:.: ..::||..|||||.: ::|..|||.....::::.::..|.:.
 Frog   406 GDDYYSYDETKREMEDDYPKSIDDEFTGVEGNIDAAVE-VNGFIYFFSGPKAYKYDTEKEDVVNI 469

  Fly   696 RAKLSARRWMQC 707
               :.:..|:.|
 Frog   470 ---VKSSSWIGC 478

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mmp2	NP_995788.1	PG_binding_1	52..103	CDD:460223	14/50 (28%)
		Peptidase_M10	143..301	CDD:425668	70/159 (44%)
		HX	513..707	CDD:238046	54/197 (27%)
mmp20	XP_012813779.1	PG_binding_1	37..94	CDD:460223	14/50 (28%)
		Peptidase_M10	115..270	CDD:425668	70/159 (44%)
		HX	289..478	CDD:238046	54/197 (27%)