Protein Alignment Mmp2 and mmp25

DIOPT Version :9

• Sequence 1: NP_995788.1
• Gene: Mmp2 / 35997
• FlyBaseID: FBgn0033438
• Length: 758
• Species: Drosophila melanogaster
• Sequence 2: XP_031749610.1
• Gene: mmp25 / 100379875
• XenbaseID: XB-GENE-5944489
• Length: 545
• Species: Xenopus tropicalis
• Alignment Length: 729
• Identity: 214/729 - (29%)
• Similarity: 301/729 - (41%)
• Gaps: 231/729 - (31%)

  Fly    45 ISEDIMYNYLMQFDYLPKSDLETGALRTEDQLKEAIRSLQSFGNITVTGEIDSATARLIQKPRCG 109
            ||:.:  ::|.::.|||..|..:...:|.:.|:||::::|....:..|||:|.||.|::.||||.
 Frog    23 ISKGV--DWLTRYGYLPPPDPFSARQQTLEGLREAVKAMQRVAGLPETGELDDATVRMMNKPRCS 85

  Fly   110 VGDRRSADSFSPDNLYHEIGSNVRVRRFALQGPKWSRTDLTWSMVNRSMPDASKVER-MVQTALD 173
            :          ||.:....|.:.|.:|:||.|..|.:..|||.:.|.....:..|.| ::.|||.
 Frog    86 L----------PDIIMRPEGRSRRNKRYALSGSVWDKKLLTWRLENSPNTMSQDVSRTLIGTALA 140

  Fly   174 VWANHSKLTFREVYSDQADIQILFARRAHGDGYKFDGPGQVLAHAFYPGEG-RGGDAHFDADETW 237
            ||:..::|.|||. .:|.||::.|...:|||||.|||.|..|.|||:||.| |.|:.|.||||:|
 Frog   141 VWSKETQLQFRET-REQPDIRVEFVTGSHGDGYPFDGQGGTLGHAFFPGVGERAGETHMDADESW 204

  Fly   238 NFDGESDDSHGTNFLNVALHELGHSLGLAHSAIPDAVMFPWYQNNEVAGN-----LPDDDRYGIQ 297
            :::.|    .||:...||:||.||||||.||:..:::|.|:||.  ..|:     ||.||..|||
 Frog   205 SYNTE----EGTDLFAVAVHEFGHSLGLYHSSSENSIMKPYYQG--TVGDPSRYRLPPDDVDGIQ 263

  Fly   298 QLYGTKEKTWGPYKPQTTTTTTTTTTMRAMIYRADKPAYWPWNNPSNNPNNDRNRARERQEEERR 362
            .|||
 Frog   264 TLYG------------------------------------------------------------- 267

  Fly   363 RQEKERRRQEEERRHQEEERRRQVEERQRQEEERWRQEQERQEEENRRRKIEHKSQWERNPSKER 427
                                                                             
 Frog   268 ----------------------------------------------------------------- 267

  Fly   428 NRPRERQEMERRRQEQERQEQERQEQEDRRRERERDRQLEWERRNRNGAREPVTPTANTTPRPTN 492
                                     |.|                  :|.|.|||||....  |..
 Frog   268 -------------------------QPD------------------SGHRPPVTPTRRAL--PPR 287

  Fly   493 KPYPTVHRQHHHHNKPRKPKPDSCMTYYDAISIIRGELFIFRGPYLWRIGTS-GLYNGYPTEIRR 556
            .|.|          .||.|.||.|.|.:|||:.||||.|.|:..|.||:.:| .|.:..|..:.|
 Frog   288 GPSP----------GPRLPFPDRCSTNFDAIANIRGEAFFFKNRYFWRVQSSRQLVSLNPAHLNR 342

  Fly   557 HWSALPENLTKVDAVYE-NKQRQIVFFIGREYYVFNSVMLAPGFPKPLASLGLPPTLTHIDASFV 620
            .|..||.:|.|:||||| ....:|||..|..|:||...::.||:|:|||..||  ....:||:||
 Frog   343 FWLGLPPDLPKLDAVYERTNDSKIVFISGTSYWVFKDTLVEPGYPRPLADFGL--NTDGVDAAFV 405

  Fly   621 WGHNNRTYMTSGTLYWRIDDYTGQVELDYPRDMSIWSGVGYNIDAAFQYLDGKTYFFKNLGYWEF 685
            |.||.:||.....|:||.|:..||::..||:|.|:|.||..|||....:.:|.|||||...||:|
 Frog   406 WKHNGKTYFFRKNLFWRFDEKRGQMDSGYPKDSSLWQGVPPNIDDIISWENGDTYFFKGTQYWKF 470

  Fly   686 NDDRMKVAHARAKLSARRWMQCARSANEVDDEQRWTASLVSEGEE---------TGRSGSRELRI 741
            ....::......:.:|..||.|......|..:       ..||.:         .||:.:.|:.
 Frog   471 QGGNVEADPGYPRSTALNWMYCPLEGPAVPTD-------APEGRDQRGCSCTCTDGRNSASEIG- 527

  Fly   742 NHFILSILLLAIAN 755
               ||....||.|:
 Frog   528 ---ILGAAWLAFAS 538

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mmp2	NP_995788.1	Peptidase_M10	143..301	CDD:278824	72/164 (44%)
		ZnMc_MMP	143..301	CDD:239805	72/164 (44%)
		HX	513..707	CDD:238046	82/195 (42%)
mmp25	XP_031749610.1	PG_binding_1	29..79	CDD:396175	17/49 (35%)
		ZnMc_MMP	110..267	CDD:239805	72/163 (44%)
		HX	298..492	CDD:238046	82/195 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	47	1.000	Domainoid score	I11824
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	358	1.000	Inparanoid score	I2167
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1075463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3504
SonicParanoid	1	1.000	-	-		X44
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.000