Protein Alignment Mmp2 and mmp25b

DIOPT Version :9

• Sequence 1: NP_995788.1
• Gene: Mmp2 / 35997
• FlyBaseID: FBgn0033438
• Length: 758
• Species: Drosophila melanogaster
• Sequence 2: XP_002663942.1
• Gene: mmp25b / 100333601
• ZFINID: ZDB-GENE-100308-4
• Length: 573
• Species: Danio rerio
• Alignment Length: 715
• Identity: 204/715 - (28%)
• Similarity: 297/715 - (41%)
• Gaps: 228/715 - (31%)

  Fly    34 AATRSKKAKTAISEDIMYNYLMQFDYLPKSDLETGALRTEDQLKEAIRSLQSFGNITVTGEIDSA 98
            :|..|...|...|..:  ::|.::.|||..|..||.|:::|.::.|||.:|.|..:..||::||.
Zfish    21 SAVHSAPVKDQYSRGV--DWLSRYGYLPPLDPRTGQLQSKDGIERAIREMQRFAGLKETGKLDSD 83

  Fly    99 TARLIQKPRCGVGDRRSADSFSPDNLYHEIGSNVRVRRFALQGPKWSRTDLTWSMVN------RS 157
            |..|:..|||.:.|....:    |.|     ...|.:|:|..|.:|:::|:|||:.|      |.
Zfish    84 TLTLMNTPRCSLPDIIGIE----DKL-----KKRRRKRYATTGLRWTKSDITWSVQNYPSVHKRL 139

  Fly   158 MPDASKVERMVQTALDVWANHSKLTFREVYS---DQADIQILFARRAHGDGYKFDGPGQVLAHAF 219
            .|  ::|:.::..||..|::.:.|.|....|   |:|||:|.|||..|.|||.|||.|..|||||
Zfish   140 TP--TQVDPIISYALKAWSDVTNLNFYGASSSEKDRADIRISFARSLHDDGYPFDGKGGTLAHAF 202

  Fly   220 YPGEGR-GGDAHFDADETWNFDGESDDSHGTNFLNVALHELGHSLGLAHSAIPDAVMFPWYQNNE 283
            :|||.. .||.|||.||.|.:..||    ||:...||:||.||:|||:||:...::|.|:||.:
Zfish   203 FPGESDVAGDTHFDDDEIWTYLDES----GTDLFAVAVHEFGHALGLSHSSSSPSIMKPYYQGS- 262

  Fly   284 VAGN-----LPDDDRYGIQQLYGTKEKTWGPYKPQTTTTTTTTTTMRAMIYRADKPAYWPWNNPS 343
             .|:     ||||||..||.|||.|                                   .::|:
Zfish   263 -VGDVGSYILPDDDREAIQSLYGRK-----------------------------------ISSPT 291

  Fly   344 NNPNNDRNRARERQEEERRRQEKERRRQEEERRHQEEERRRQVEERQRQEEERWRQEQERQEEEN 408
            .:||.
Zfish   292 PSPNK------------------------------------------------------------ 296

  Fly   409 RRRKIEHKSQWERNPSKERNRPRERQEMERRRQEQERQEQERQEQEDRRRERERDRQLEWERRNR 473
                                                                             
Zfish   297 ----------------------------------------------------------------- 296

  Fly   474 NGAREPVTPTANTTPRPTNKPYPTVHRQHHHHNKPRKPKP---DSCMTYYDAISIIRGELFIFRG 535
                    ||:: .|:|. ..||         ..|.||.|   :.|...:||::.:|||:|.|:|
Zfish   297 --------PTSH-LPKPP-ATYP---------KGPVKPDPSIQNRCEGGFDAVANLRGEVFFFKG 342

  Fly   536 PYLWRIGTSG-LYNGYPTEIRRHWSALPENLTKVDAVYENK-QRQIVFFIGREYYVFNSVMLAPG 598
            ||.|||..:| |.:..|..|:..|..||....|||||||.| ...|:||||.:|:||.:..:.||
Zfish   343 PYFWRIQRTGSLVSFQPAHIKNFWMGLPPTTNKVDAVYERKVDNAIIFFIGSQYWVFKNTEVLPG 407

  Fly   599 FPKPLASLGL----PPTLTHIDASFVWGHNNRTYMTSGTLYWRIDDYTGQVEL-----DYPRDMS 654
            :|:||:..|:    ...:..:||:|:|.||.:||:.||..:||..: ..:.||     .|||:.:
Zfish   408 YPRPLSDWGMITQDGRKVMRVDAAFIWAHNGKTYIFSGGEFWRFSE-GRETELRGPDTGYPRNTN 471

  Fly   655 IWSGVGYNIDAAFQYLDGKTYFFKNLGYWEFNDDRMKVAHARAKLSARRWMQCARSANEVDDEQR 719
            :|.|...|.|....:..|..||||:..||...:..|.......|.:|..||.|.:...:..:..|
Zfish   472 LWKGAPSNPDDVITWGQGDAYFFKDNSYWVLKNGEMDQTSVTKKSTAVDWMMCQQETTKAPESPR 536

  Fly   720  719
            Zfish   537  536

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mmp2	NP_995788.1	Peptidase_M10	143..301	CDD:278824	76/172 (44%)
		ZnMc_MMP	143..301	CDD:239805	76/172 (44%)
		HX	513..707	CDD:238046	77/207 (37%)
mmp25b	XP_002663942.1	PG_binding_1	38..88	CDD:279773	19/49 (39%)
		Peptidase_M10	119..284	CDD:278824	76/172 (44%)
		ZnMc_MMP	119..284	CDD:239805	76/172 (44%)
		HX	321..524	CDD:238046	76/203 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	47	1.000	Domainoid score	I11983
eggNOG	1	0.900	-	-		E1_KOG1565
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	347	1.000	Inparanoid score	I2272
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1075463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X44
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.870