Protein Alignment Mmp2 and mmp19

DIOPT Version :9

• Sequence 1: NP_995788.1
• Gene: Mmp2 / 35997
• FlyBaseID: FBgn0033438
• Length: 758
• Species: Drosophila melanogaster
• Sequence 2: XP_031753026.1
• Gene: mmp19 / 100127631
• XenbaseID: XB-GENE-5932824
• Length: 476
• Species: Xenopus tropicalis
• Alignment Length: 713
• Identity: 182/713 - (25%)
• Similarity: 262/713 - (36%)
• Gaps: 258/713 - (36%)

  Fly     5 YVLATLLALFAQSMCIQELSLPPEGSHSTAATRSKKAKTAISEDIMYNYLMQFDYLPKSDLETGA 69
            ::|...|..|..:|.|:    |..|         ::||         .||.||.||.| .||:.
 Frog     8 FLLLGTLPFFVYAMHIE----PSSG---------EEAK---------RYLQQFGYLQK-PLESD- 48

  Fly    70 LRTED----QLKEAIRSLQSFGNITVTGEIDSATARLIQKPRCGVGDRRSADSFSPDNLYHEIGS 130
              |||    :::||:|..|...::..||.:|..|...:::|||||     .|.|
 Frog    49 --TEDFSSEEVQEALRIFQLSTHLPGTGVLDEDTIDKMRQPRCGV-----EDPF----------- 95

  Fly   131 NVRVRRFALQGPKWSRTDLTWSMVNRSMPDAS--KVERMVQTALDVWANHSKLTFREVYSDQADI 193
            |.:..|:.|.| :|.:.:||:.:.|.: ||.|  .....:......|::.:.|||:||...:|||
 Frog    96 NQKTLRYLLLG-RWRKKNLTYRIYNYT-PDMSLAAARSAILAGFKYWSDVTPLTFKEVTRGRADI 158

  Fly   194 QILFARRAHGDGYKFDGPGQVLAHAFYPGEGRGGDAHFDADETWNFDGESDDSHGTNFLNVALHE 258
            :|.|.||.:|....|||||:|||||..|   ..|..|||.||.|. :|..:   |.|...:|.||
 Frog   159 RISFHRRGNGCSRPFDGPGKVLAHADIP---ELGTVHFDEDELWT-EGTYE---GVNLRIIAAHE 216

  Fly   259 LGHSLGLAHSAIPDAVMFPWYQNNEVAGNLPDDDRYGIQQLYGTKEKTWGPYKPQTTTTTTTTTT 323
            |||:|||.||....|:|.|.|...:....|.|||..|||.|||.|:|.
 Frog   217 LGHALGLGHSRFRSALMAPIYFGYKPNFRLHDDDVKGIQALYGKKDKI----------------- 264

  Fly   324 MRAMIYRADKPAYWPWNNPSNNPNNDRNRARERQEEERRRQEKERRRQEEERRHQEEERRRQVEE 388
                                                                   |||.....||
 Frog   265 -------------------------------------------------------EEEEVVTTEE 274

  Fly   389 RQRQEEERWRQEQERQEEENRRRKIEHKSQWERNPSKERNRPRERQEMERRRQEQERQEQERQEQ 453
                                                                             
 Frog   275 ----------------------------------------------------------------- 274

  Fly   454 EDRRRERERDRQLEWERRNRNGAREPVTPTANTTPRPTNKPYPTVHRQHHHHNKPRKPKPDSCMT 518
                                        |..:..|.||:.                  .||.|..
 Frog   275 ----------------------------PAISAEPTPTSL------------------TPDPCND 293

  Fly   519 YYDAISI-IRGELFIFRGPYLWRI---GTSGLYNGYPTEIRRHWSALPENLTKVDAVYENKQRQI 579
            ..|||.: ..|:.:.|:|.|:|.|   |.|.|     ..|:..|..||.|:..  ||:..:.::.
 Frog   294 NLDAIILGPYGKTYAFKGDYVWTITDFGISPL-----IRIQSLWKGLPGNIDA--AVHSPRTQRT 351

  Fly   580 VFFIGREYYVFNSVMLAPGFPKPLASLGLPPTLTHIDASFVWGHNNRTYMTSGTLYWRIDDYTGQ 644
            .||.|.:.:|:.:..|.||:||.:..  :||   :|:|:..|..|.:.::..|..||:.|: .|.
 Frog   352 YFFKGDKLWVYTNFKLNPGYPKLITR--VPP---NINAALYWEVNKKIFLFKGDGYWQWDE-LGW 410

  Fly   645 VELDYPRDMSIWSGVGYNIDAAFQYLDGKTYFFKNLGYWEFNDDRMKVAHARAKLSARRWMQC 707
            ..|...:..|:::|:...:|||..:.:||.||||...||..| .:::|........|.|||||
 Frog   411 SNLSSKKISSLFTGIPSQLDAAVTWKNGKIYFFKGDKYWRVN-KQLRVERGYPLSKAERWMQC 472

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mmp2	NP_995788.1	Peptidase_M10	143..301	CDD:278824	65/159 (41%)
		ZnMc_MMP	143..301	CDD:239805	65/159 (41%)
		HX	513..707	CDD:238046	62/197 (31%)
mmp19	XP_031753026.1	PG_binding_1	29..84	CDD:396175	22/67 (33%)
		ZnMc_MMP	107..259	CDD:239805	65/159 (41%)
		HX	288..472	CDD:238046	62/197 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1075463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10201
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X44
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	5.020