Protein Alignment CG12926 and TTPA

DIOPT Version :10

• Sequence 1: NP_610510.2
• Gene: CG12926 / 35996
• FlyBaseID: FBgn0033437
• Length: 313
• Species: Drosophila melanogaster
• Sequence 2: NP_001400347.1
• Gene: TTPA / 7274
• HGNCID: 12404
• Length: 317
• Species: Homo sapiens
• Alignment Length: 323
• Identity: 77/323 - (23%)
• Similarity: 127/323 - (39%)
• Gaps: 82/323 - (25%)

  Fly     1 MSEAYSNSIRSLSPELAKKAHDELGEIPDR---IDEDIETLRTWISKQPHLKARQDA-------- 54
            |:||.|.          ..|..:|..:||.   :...:..||.        :||:..
Human     1 MAEARSQ----------PSAGPQLNALPDHSPLLQPGLAALRR--------RAREAGVPLAPLPL 47

  Fly    55 --QFLVAFLRGCKYSLEKTKLKLDNFYAMRGAVPE----LYKNRIV-----------------GE 96
              .||:.|||...:.|:.....|.|:|..|...||    |:...|:                 |.
Human    48 TDSFLLRFLRARDFDLDLAWRLLKNYYKWRAECPEISADLHPRSIIGLLKAGYHGVLRSRDPTGS 112

  Fly    97 KQL-------SILDTG-----------CLLRLPQPLQADGPRIHISRYG---QYDSKKYSIAEVV 140
            |.|       |:...|           ||     |..:|.|.......|   .:|.|.::..:|.
Human   113 KVLIYRIESCSVAQAGEQWAISTHYNLCL-----PSSSDSPASASQVAGTTAHWDPKVFTAYDVF 172

  Fly   141 QVNTMLGEIQIREDDNAMISGFVEIIDMKGVGAGHLFQFDAVLVKKLAVLGDKAYPYRPKGFHFV 205
            :|:.:..|:.::|.:... :|...|.|::|....|.||....:.||:|.:...::|.:.:|.|.:
Human   173 RVSLITSELIVQEVETQR-NGIKAIFDLEGWQFSHAFQITPSVAKKIAAVLTDSFPLKVRGIHLI 236

  Fly   206 NAPSSAEKFMSIAKSLMSEKIRKRFHIHSK--LDSLYKYVPKECLPAEYGGSNGTIQDVVSTW 266
            |.|.......|:.|..::|||::|.|:|..  ..||.::.| :.||.||||...:::|:...|
Human   237 NEPVIFHAVFSMIKPFLTEKIKERIHMHGNNYKQSLLQHFP-DILPLEYGGEEFSMEDICQEW 298

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12926	NP_610510.2	CRAL_TRIO_N	32..77	CDD:215024	11/54 (20%)
		CRAL_TRIO	117..254	CDD:459890	39/141 (28%)
TTPA	NP_001400347.1	CRAL_TRIO_N	<40..73	CDD:215024	7/32 (22%)
		CRAL_TRIO	159..286	CDD:459890	36/128 (28%)