DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12926 and Sec14l5

DIOPT Version :9

Sequence 1:	NP_610510.2	Gene:	CG12926 / 35996	FlyBaseID:	FBgn0033437	Length:	313	Species:	Drosophila melanogaster
Sequence 2:	NP_001121197.1	Gene:	Sec14l5 / 665119	MGIID:	3616084	Length:	696	Species:	Mus musculus

Alignment Length:	266	Identity:	63/266 - (23%)
Similarity:	108/266 - (40%)	Gaps:	55/266 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 LGEIPDRIDEDIETLRTWISKQPHLKARQDAQFLVAFLRGCKYSLEKTKLKLDNFYAMRGAVPEL 88
            ||.:....:..:..||.|:.:....|..:| :.::.|||...:.|:|.:..|....:.|
Mouse   235 LGHLSPMQESCLVQLRHWLQETHKGKIPKD-EHILRFLRARDFHLDKARDMLCQSLSWR------ 292

  Fly    89 YKNRIVGEKQLSI---LDTGCLLRLPQPLQ-----------ADGPRIHISRYGQYDSK------- 132
                    ||..:   |.|   .|.|.|||           .||..::|.|.||.|:|
Mouse   293 --------KQHQVDLLLQT---WRPPPPLQEFYAGGWHYQDIDGRPLYILRLGQMDTKGLMKAVG 346

  Fly   133 -KYSIAEVVQVNTMLGEIQIREDDNAM-----ISGFVEIIDMKGVGAGHLFQFDA-VLVKKLAVL 190
             :..:..|:.||.   |.|.|.:.|..     ||.:..::|::|:...||::... .|::.:.|:
Mouse   347 EEALLQHVLSVNE---EGQKRCEGNTRQFGRPISSWTCLLDLEGLNMRHLWRPGVKALLRMIEVV 408

  Fly   191 GDKAYPYRPKGFHFVNAPSSAEKFMSIAKSLMSEKIRKRFHIHSKLD-----SLYKYVPKECLPA 250
            .|. ||........|.||.......::....::|..|::|.|:|..:     .|..|:.|:.:|.
Mouse   409 EDN-YPETLGRLLIVRAPRVFPVLWTLVSPFINENTRRKFLIYSGSNYQGPGGLVDYLDKDVIPD 472

  Fly   251 EYGGSN 256
            ..||.:
Mouse   473 FLGGES 478

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12926	NP_610510.2	CRAL_TRIO_N	32..77	CDD:215024	11/44 (25%)
CG12926	NP_610510.2	SEC14	117..254	CDD:238099	38/155 (25%)
Sec14l5	NP_001121197.1	PRELI	17..173	CDD:368069
		CRAL_TRIO_N	243..288	CDD:215024	11/45 (24%)
		SEC14	306..479	CDD:214706	44/177 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810