Protein Alignment CG12926 and Ttpa

DIOPT Version :9

• Sequence 1: NP_610510.2
• Gene: CG12926 / 35996
• FlyBaseID: FBgn0033437
• Length: 313
• Species: Drosophila melanogaster
• Sequence 2: NP_056582.1
• Gene: Ttpa / 50500
• MGIID: 1354168
• Length: 278
• Species: Mus musculus
• Alignment Length: 261
• Identity: 70/261 - (26%)
• Similarity: 122/261 - (46%)
• Gaps: 31/261 - (11%)

  Fly    23 ELGEIPDR---IDEDIETLRTWISK-------QPHLKARQDAQFLVAFLRGCKYSLEKTKLKLDN 77
            :|.|:||.   :...:..||..:.:       ||...|     ||:.|||...:.|:.....:.|
Mouse    13 QLNELPDHSPLLQPGLAELRRRVQEAGVPQTPQPLTDA-----FLLRFLRARDFDLDLAWRLMKN 72

  Fly    78 FYAMRGAVPEL---YKNRIVGEKQLSILDTGC--LLRLPQPLQADGPRIHISRYGQYDSKKYSIA 137
            :|..|...|||   .:.|.:    |.:|..|.  :||   ...:.|.|:.|.|...:|.|.::..
Mouse    73 YYKWRAECPELSADLRPRSI----LGLLKAGYHGVLR---SRDSTGSRVLIYRIAYWDPKVFTAY 130

  Fly   138 EVVQVNTMLGEIQIREDDNAMISGFVEIIDMKGVGAGHLFQFDAVLVKKLAVLGDKAYPYRPKGF 202
            :|.:|:.:..|:.::|.:... :|...|.|::|....|.||....:.||:|.:...::|.:.:|.
Mouse   131 DVFRVSLITSELIVQEVETQR-NGVKAIFDLEGWQVSHAFQITPSVAKKIAAVLTDSFPLKVRGI 194

  Fly   203 HFVNAPSSAEKFMSIAKSLMSEKIRKRFHIHSK--LDSLYKYVPKECLPAEYGGSNGTIQDVVST 265
            |.:|.|.......|:.|..::|||:.|.|:|..  ..|:.::.| :.||.||||...:::|:...
Mouse   195 HLINEPVIFHAVFSMIKPFLTEKIKDRIHLHGNNYKSSMLQHFP-DILPREYGGKEFSMEDICQE 258

  Fly   266 W 266
            |
Mouse   259 W 259

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12926	NP_610510.2	CRAL_TRIO_N	32..77	CDD:215024	11/51 (22%)
		SEC14	117..254	CDD:238099	39/138 (28%)
Ttpa	NP_056582.1	CRAL_TRIO_N	25..73	CDD:215024	11/52 (21%)
		CRAL_TRIO	99..248	CDD:279044	43/153 (28%)
		Phosphatidylinositol 3,4-bisphosphate binding. /evidence=ECO:0000269|PubMed:23599266, ECO:0007744|PDB:3W67	190..192		0/1 (0%)
		Phosphatidylinositol 4,5-bisphosphate binding. /evidence=ECO:0000269|PubMed:23599266, ECO:0007744|PDB:3W68	208..211		1/2 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D559280at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10174
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X106
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920