DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12926 and CG33523

DIOPT Version :9

Sequence 1:	NP_610510.2	Gene:	CG12926 / 35996	FlyBaseID:	FBgn0033437	Length:	313	Species:	Drosophila melanogaster
Sequence 2:	NP_001261457.1	Gene:	CG33523 / 38668	FlyBaseID:	FBgn0053523	Length:	654	Species:	Drosophila melanogaster

Alignment Length:	276	Identity:	52/276 - (18%)
Similarity:	100/276 - (36%)	Gaps:	73/276 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 IRSLSPELAKKAHDELGEIPDRIDEDIETLRTWISKQPHL--------KARQDAQFLVAFLRGCK 65
            ::..:|:       ::.|:.||.:      |.:.|..|..        :.|.|..:|..||.  .
  Fly     5 VKETTPQ-------QIEELRDRFN------RKYASSPPAAPFHPTDIDRIRNDHLWLQRFLE--M 54

  Fly    66 YSLEKTKLKLDNFYAMRGAVPELYKNRI---------VGEKQLS--ILDTGCLLRLPQPLQADGP 119
            |.|:           |..:...|::..|         :.|.:|:  .|..|.:  .......||.
  Fly    55 YDLD-----------METSFNSLWETCILRQSTGANDIDESELNQEYLKEGSV--FVHNTDVDGK 106

  Fly   120 RIHISRYGQYDSKKYSIAEVVQVNTMLGEIQIREDDNAMISGFVEIIDMKGVGAGHLFQFDAVLV 184
            .:.:.|...: ||..::.|::::.....|...||.....::.|   .||.|..   |...|...|
  Fly   107 PLLVFRVKMH-SKSKNLDELIRIVVYWVERTQREQHLTQLTIF---FDMSGTS---LASMDLEFV 164

  Fly   185 KKLAVLGDKAYPYRPKGFHFV---------NAPSSAEKFMSIAKSLMSEKIRKRFHIHSKLDSLY 240
            |::.....:.|   |...:::         ||.      ..:.|:::..|..:...:.||.| :.
  Fly   165 KRIVETFKQFY---PNSLNYILVYELGWVLNAA------FKVIKAVLPPKAVEILKMISKKD-IN 219

  Fly   241 KYVPKECLPAEYGGSN 256
            :|:.|:...|.:||.:
  Fly   220 QYINKDNCLAIWGGED 235

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12926	NP_610510.2	CRAL_TRIO_N	32..77	CDD:215024	10/52 (19%)
CG12926	NP_610510.2	SEC14	117..254	CDD:238099	29/145 (20%)
CG33523	NP_001261457.1	CRAL_TRIO	94..234	CDD:279044	31/158 (20%)
CG33523	NP_001261457.1	Motile_Sperm	293..396	CDD:279029
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900