DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12926 and Ku80

DIOPT Version :9

Sequence 1:	NP_610510.2	Gene:	CG12926 / 35996	FlyBaseID:	FBgn0033437	Length:	313	Species:	Drosophila melanogaster
Sequence 2:	NP_609767.2	Gene:	Ku80 / 34930	FlyBaseID:	FBgn0041627	Length:	699	Species:	Drosophila melanogaster

Alignment Length:	296	Identity:	53/296 - (17%)
Similarity:	101/296 - (34%)	Gaps:	95/296 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 LKARQDAQFLVAFLRGCKYSLEKTKLKLDNFYAMRGAVPELYKNRIVGEKQ--LSILDTGCLLRL 110
            :.:.::...:|..:|.|  :.|:.|||      ....|.|:.|::||.:::  :|.:..||
  Fly     1 MASNKECLIIVLDVRTC--AAEEVKLK------SAKCVAEILKDKIVCDRKDYVSFVLVGC---- 53

  Fly   111 PQPLQADGPRIHISRYGQYDSKKYSIAEVVQVNTM-LGEIQIRE----------------DDNAM 158
                               |:.:....:....|.: .||.::..                :|...
  Fly    54 -------------------DTDEIKTEDASHPNVLPFGEPRLCSWQLLLEFFQFVNKTACEDGEW 99

  Fly   159 ISGFVEIIDMKGVGAGHLFQFDAVLVKKLAVLGDKAYPYRPKGFHFVNAPSSAEKFMSIAKSLMS 223
            ::|....::::.|....     .|..:::.:|           |.|.:.|...|||..|...|:.
  Fly   100 LNGLQAALELQNVATTL-----RVARRRILLL-----------FDFNDFPQDYEKFNEITDELLG 148

  Fly   224 EKIRKRFHIH----------SKLDSLYKYVPKECLPAEYGGSNGTIQDVVSTWRTKLLAYKPFFE 278
            |.|......|          |:..:::.: .::|.|.|.......: .:|......|.::|
  Fly   149 ENIELIVGTHNIAYIDNAITSQPQAIFNF-SRKCGPDELNNQKYAL-SLVPRCNATLCSFK---- 207

  Fly   279 EEASYGT-----------NEKLRRGQPVSAESLFGI 303
             ||.:..           |.||..|..:|. ||.||
  Fly   208 -EALHTVFKVTNRRPWVWNAKLNIGSKISI-SLQGI 241

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12926	NP_610510.2	CRAL_TRIO_N	32..77	CDD:215024	7/28 (25%)
CG12926	NP_610510.2	SEC14	117..254	CDD:238099	24/163 (15%)
Ku80	NP_609767.2	Ku_N	7..213	CDD:281693	44/259 (17%)
		KU80	221..524	CDD:238445	9/22 (41%)
		Ku_PK_bind	562..663	CDD:285938
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900