DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG12926 and retm

DIOPT Version :9

Sequence 1:	NP_610510.2	Gene:	CG12926 / 35996	FlyBaseID:	FBgn0033437	Length:	313	Species:	Drosophila melanogaster
Sequence 2:	NP_001260132.1	Gene:	retm / 33899	FlyBaseID:	FBgn0031814	Length:	707	Species:	Drosophila melanogaster

Alignment Length:	270	Identity:	59/270 - (21%)
Similarity:	105/270 - (38%)	Gaps:	45/270 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 SNSIRSLSPELAKKAHDELGEIPDRIDEDIETLRTWISKQPHLKARQDAQFLVAFLRGCKYSLEK 70
            :.|:..|||....|.. ||.::.|.:| |:|.:.::.:....|.|| |.....|:...|.....:
  Fly   211 ARSLGQLSPMQESKLL-ELRKMLDGVD-DLERVPSYQTILRFLAAR-DWHVSQAYAMLCDSLRWR 272

  Fly    71 TKLKLDNFYAMRGAVPELYKNRIVGEKQLSILDTGCLLRLP---QPLQADGPRIHISRYGQYDSK 132
            .:.::|...|      |..|..:|.|            ..|   ..|..||..::|.|.|..|.|
  Fly   273 REHRIDALLA------EYSKPAVVVE------------HFPGGWHHLDKDGRPVYILRLGHMDVK 319

  Fly   133 KYSIAEVVQVNTMLG-EIQIREDDNAMISGFVE-----------IIDMKGVGAGHLFQFDAVLVK 185
              .:.:.:.::.:|. .:.|.|:....|:...|           ::|::|:...||::.....:.
  Fly   320 --GLLKSLGMDGLLRLALHICEEGIQKINESAERLEKPVLNWSLLVDLEGLSMRHLWRPGIKALL 382

  Fly   186 KLAVLGDKAYPYRPKGFHFVNAPSSAEKFMSIAKSLMSEKIRKRFHI------HSKLDSLYKYVP 244
            .:....::.||........|.||.......:|..:.:.|..|.:|..      |.| |.|.:|:.
  Fly   383 NIIETVERNYPETMGRVLVVRAPRVFPIAWTIVSAFIDEHTRSKFLFYGPDCAHMK-DGLAQYLD 446

  Fly   245 KECLPAEYGG 254
            :|.:|...||
  Fly   447 EEIVPDFLGG 456

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12926	NP_610510.2	CRAL_TRIO_N	32..77	CDD:215024	9/44 (20%)
CG12926	NP_610510.2	SEC14	117..254	CDD:238099	32/154 (21%)
retm	NP_001260132.1	PRELI	17..173	CDD:282550
		CRAL_TRIO_N	222..268	CDD:215024	13/48 (27%)
		CRAL_TRIO	293..456	CDD:279044	34/165 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810