DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG12926 and SEC14L2

DIOPT Version :9

Sequence 1:NP_610510.2 Gene:CG12926 / 35996 FlyBaseID:FBgn0033437 Length:313 Species:Drosophila melanogaster
Sequence 2:NP_036561.1 Gene:SEC14L2 / 23541 HGNCID:10699 Length:403 Species:Homo sapiens


Alignment Length:270 Identity:59/270 - (21%)
Similarity:106/270 - (39%) Gaps:47/270 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly     6 SNSIRSLSPELAKKAHDELGEIPDRIDEDIETLRTWISKQPHLKARQDAQFLVAFLRGCKYSLEK 70
            |..:..|||    :..:.|.:..:.:.:.:..|           ...|..||:.:||...:.|:|
Human     2 SGRVGDLSP----RQKEALAKFRENVQDVLPAL-----------PNPDDYFLLRWLRARSFDLQK 51

  Fly    71 TKLKL------------DNFYAMRGAVPELYKNRIVGEKQLSILDTGCLL--RLPQPLQADGPRI 121
            ::..|            ||..:.:  .||:.:..:.|......|| ||.:  .:..||.|.|...
Human    52 SEAMLRKHVEFRKQKDIDNIISWQ--PPEVIQQYLSGGMCGYDLD-GCPVWYDIIGPLDAKGLLF 113

  Fly   122 HISRYGQYDSK----KYSIAEVVQVNTMLGEIQIREDDNAMISGFVEIIDMKGVGAGHLFQFDAV 182
            ..|:.....:|    :..:.|.....|.||    |:.:...|     |.|.:|:|..||::....
Human   114 SASKQDLLRTKMRECELLLQECAHQTTKLG----RKVETITI-----IYDCEGLGLKHLWKPAVE 169

  Fly   183 LVKKLAVLGDKAYPYRPKGFHFVNAPSSAEKFMSIAKSLMSEKIRKRFHI--HSKLDSLYKYVPK 245
            ...:...:.::.||...|....|.||.......::.|..:||..||:..:  .:..:.|.|::..
Human   170 AYGEFLCMFEENYPETLKRLFVVKAPKLFPVAYNLIKPFLSEDTRKKIMVLGANWKEVLLKHISP 234

  Fly   246 ECLPAEYGGS 255
            :.:|.||||:
Human   235 DQVPVEYGGT 244

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG12926NP_610510.2 CRAL_TRIO_N 32..77 CDD:215024 9/56 (16%)
SEC14 117..254 CDD:238099 31/142 (22%)
SEC14L2NP_036561.1 CRAL_TRIO_N 13..59 CDD:215024 10/56 (18%)
SEC14 76..244 CDD:214706 42/177 (24%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1471
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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