Protein Alignment CG12926 and CLVS2

DIOPT Version :10

• Sequence 1: NP_610510.2
• Gene: CG12926 / 35996
• FlyBaseID: FBgn0033437
• Length: 313
• Species: Drosophila melanogaster
• Sequence 2: NP_001010852.2
• Gene: CLVS2 / 134829
• HGNCID: 23046
• Length: 327
• Species: Homo sapiens
• Alignment Length: 318
• Identity: 80/318 - (25%)
• Similarity: 143/318 - (44%)
• Gaps: 56/318 - (17%)

  Fly    12 LSPELAKKAHDELGEIPDRIDEDIETLRTWISKQPHLK-ARQDAQFLVAFLRGCKYSLEKTKLKL 75
            ||||..:||..||.|.||.:.:||:.:|..:..:|.:. .|.|..|::.|||..|:...:....|
Human     8 LSPETLEKARLELNENPDTLHQDIQEVRDMVITRPDIGFLRTDDAFILRFLRARKFHHFEAFRLL 72

  Fly    76 DNFYAMRGAVPELYKNRIVGEKQLSILDTGCLLRLPQPLQ--ADGPRIHISRYGQ---------Y 129
            ..::..|....:::|:       ....|.|    :.|.|:  ..|...::..||:         :
Human    73 AQYFEYRQQNLDMFKS-------FKATDPG----IKQALKDGFPGGLANLDHYGRKILVLFAANW 126

  Fly   130 DSKKYSIAEVVQVNTMLGEIQIREDDNAMISGFVEIIDMKGVGAGHLFQFDAV-----LVKKLAV 189
            |..:|::.::::...:..|..| ||....::|||.|||...      |.|...     .:.:||:
Human   127 DQSRYTLVDILRAILLSLEAMI-EDPELQVNGFVLIIDWSN------FTFKQASKLTPSMLRLAI 184

  Fly   190 LG-DKAYPYRPKGFHFVNAPSSAEKFMSIAKSLMSEKIRKRFHIH-SKLDSLYKYVPKECLPAEY 252
            .| ..::|.|..|.||||.|.......::.:..:.||.|||..:| :.|:||::.:..|.||:|:
Human   185 EGLQDSFPARFGGIHFVNQPWYIHALYTVIRPFLKEKTRKRIFLHGNNLNSLHQLIHPEILPSEF 249

  Fly   253 GGSNGTIQDVVSTWRTKLLAYKPFFEEEASYGTN---------------EKLRRGQPV 295
            ||......  :.||...||.::  :::::.|..:               :.::|.|.|
Human   250 GGMLPPYD--MGTWARTLLDHE--YDDDSEYNVDSYSMPVKEVEKELSPKSMKRSQSV 303

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12926	NP_610510.2	CRAL_TRIO_N	32..77	CDD:215024	12/45 (27%)
		CRAL_TRIO	117..254	CDD:459890	41/152 (27%)
CLVS2	NP_001010852.2	CRAL_TRIO_N	29..75	CDD:215024	12/45 (27%)
		SEC14	101..251	CDD:469559	41/156 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	287..327		3/17 (18%)