DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG12926 and Sec14l2

DIOPT Version :9

Sequence 1:	NP_610510.2	Gene:	CG12926 / 35996	FlyBaseID:	FBgn0033437	Length:	313	Species:	Drosophila melanogaster
Sequence 2:	NP_446253.2	Gene:	Sec14l2 / 116486	RGDID:	621779	Length:	403	Species:	Rattus norvegicus

Alignment Length:	268	Identity:	58/268 - (21%)
Similarity:	101/268 - (37%)	Gaps:	43/268 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 SNSIRSLSPELAKKAHDELGEIPDRIDEDIETLRTWISKQPHLKARQDAQFLVAFLRGCKYSLEK 70
            |..:..|||    |..:.|.:..:.:.:.:..|           ...|..||:.:||...:.|:|
  Rat     2 SGRVGDLSP----KQEEALAKFRENVQDVLPAL-----------PNPDDYFLLRWLRARSFDLQK 51

  Fly    71 TKLKLDNFYAMR----------GAVPELYKNRIVGEKQLSILDTGCLL--RLPQPLQADGPRIHI 123
            ::..|......|          ...||:.:..:.|.:....|| ||.:  .:..||.|.|.....
  Rat    52 SEAMLRKHVEFRKQKDIDKIISWQPPEVIQQYLSGGRCGYDLD-GCPVWYDIIGPLDAKGLLFSA 115

  Fly   124 SRYGQYDSK----KYSIAEVVQVNTMLGEIQIREDDNAMISGFVEIIDMKGVGAGHLFQFDAVLV 184
            |:.....:|    :..:.|.......||:         .|.....|.|.:|:|..||::......
  Rat   116 SKQDLLRTKMRDCELLLQECTHQTAKLGK---------KIETITMIYDCEGLGLKHLWKPAVEAY 171

  Fly   185 KKLAVLGDKAYPYRPKGFHFVNAPSSAEKFMSIAKSLMSEKIRKRFHI--HSKLDSLYKYVPKEC 247
            .:...:.::.||...|....|.||.......::.|..:||..||:..:  .:..:.|.|::..:.
  Rat   172 GEFLTMFEENYPETLKRLFVVKAPKLFPVAYNLIKPFLSEDTRKKIMVLGANWKEVLLKHISPDQ 236

  Fly   248 LPAEYGGS 255
            ||.||||:
  Rat   237 LPVEYGGT 244

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12926	NP_610510.2	CRAL_TRIO_N	32..77	CDD:215024	9/44 (20%)
CG12926	NP_610510.2	SEC14	117..254	CDD:238099	30/142 (21%)
Sec14l2	NP_446253.2	CRAL_TRIO_N	13..59	CDD:215024	10/56 (18%)
		SEC14	76..244	CDD:214706	41/177 (23%)
		GOLD_2	300..381	CDD:290608
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810