DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG12926 and Sec14l4

DIOPT Version :9

Sequence 1:	NP_610510.2	Gene:	CG12926 / 35996	FlyBaseID:	FBgn0033437	Length:	313	Species:	Drosophila melanogaster
Sequence 2:	NP_666125.1	Gene:	Sec14l4 / 103655	MGIID:	2144095	Length:	403	Species:	Mus musculus

Alignment Length:	267	Identity:	59/267 - (22%)
Similarity:	105/267 - (39%)	Gaps:	60/267 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 ELGEIPDRIDEDI----ETLRTWISKQPHLKARQDAQFLVAFLRGCKYSLEKTKLKLDNFYAMRG 83
            ::|::..:..|.:    |||:..:...|    :.|..||:.:||...:.|:|::..|......|.
Mouse     4 QVGDLSPQQQEALARFRETLQDLLPTLP----KADDYFLLRWLRARNFDLKKSEDMLRKHVEFRN 64

  Fly    84 ----------AVPELYKNRIVGEKQLSILDTGCLLRLPQPLQADGPRIHISRYGQYD-------- 130
                      ..||:          :.:.|:|.|    .....:|..:.....|..|
Mouse    65 QQNLDQILTWQAPEV----------IQLYDSGGL----SGYDYEGCPVWFDIIGTMDPKGLFMSA 115

  Fly   131 SKKYSIAEVVQV-NTMLGEIQIREDD-NAMISGFVEIIDMKGVGAGHLF--------QFDAVLVK 185
            ||:..|.:.::| ..:|.|.:::... ...|...|.:.||:|:...||:        ||.|:|
Mouse   116 SKQDMIRKRIKVCEMLLHECELQSQKLGRKIERMVMVFDMEGLSLRHLWKPAVEVYQQFFAIL-- 178

  Fly   186 KLAVLGDKAYPYRPKGFHFVNAPSSAEKFMSIAKSLMSEKIRKRFHI--HSKLDSLYKYVPKECL 248
                  :..||...|....:.||.......::.||.|.|:.:|:..|  .:....|.|:|..:.|
Mouse   179 ------EANYPETVKNLIIIRAPKLFPVAFNLVKSFMGEETQKKIVILGGNWKQELVKFVSPDQL 237

  Fly   249 PAEYGGS 255
            |.|:||:
Mouse   238 PVEFGGT 244

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12926	NP_610510.2	CRAL_TRIO_N	32..77	CDD:215024	13/48 (27%)
CG12926	NP_610510.2	SEC14	117..254	CDD:238099	37/156 (24%)
Sec14l4	NP_666125.1	CRAL_TRIO_N	13..59	CDD:215024	13/49 (27%)
		SEC14	77..244	CDD:214706	43/188 (23%)
		GOLD_2	284..379	CDD:290608
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810