DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstT1 and TEF4

DIOPT Version :9

Sequence 1:	NP_610509.2	Gene:	GstT1 / 35995	FlyBaseID:	FBgn0050000	Length:	228	Species:	Drosophila melanogaster
Sequence 2:	NP_012842.1	Gene:	TEF4 / 853781	SGDID:	S000001564	Length:	412	Species:	Saccharomyces cerevisiae

Alignment Length:	217	Identity:	48/217 - (22%)
Similarity:	84/217 - (38%)	Gaps:	59/217 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 TDEYRSINRFQKVPAIVDGK-FQLGESVSIVRYLADKGVFSEQLYPKTLEERARV--------DE 99
            :.|:.|:...::.||.:..| .:|.|:::|..|||:: |..|       :||||:        .:
Yeast    36 SSEFASLFPLKQAPAFLGPKGLKLTEALAIQFYLANQ-VADE-------KERARLLGSDVIEKSQ 92

  Fly   100 FLEWQHFNVRLVCSLFFRQVWLLPAKGLAPAPKPESVKKLIKDVESNLGLLERLWLEKD------ 158
            .|.|.......|.|...|.  .|..|||.|..|        |||::....::.|....|
Yeast    93 ILRWASLANSDVMSNIARP--FLSFKGLIPYNK--------KDVDACFVKIDNLAAVFDARLRDY 147

  Fly   159 -FLVGDKLTVADI-------FGSSEINQMKLCQYNVNEKQFPKVAKWMERVRDATNPYY------ 209
             |:..:.:::.|:       ||.:.|...:.      ..:.|.:.:|...|  |.:|..
Yeast   148 TFVATENISLGDLHAAGSWAFGLATILGPEW------RAKHPHLMRWFNTV--AASPIVKTPFAE 204

  Fly   210 ----DEAHSFVYKTSQQAVKAK 227
                ::|.::.....|:|.|.|
Yeast   205 VKLAEKALTYTPPKKQKAEKPK 226

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstT1	NP_610509.2	GstA	5..204	CDD:223698	41/182 (23%)
		GST_N_Theta	5..80	CDD:239348	11/36 (31%)
		GST_C_Theta	93..218	CDD:198292	31/156 (20%)
TEF4	NP_012842.1	GST_N_EF1Bgamma	4..72	CDD:239342	11/35 (31%)
		GST_C_EF1Bgamma_like	89..211	CDD:198290	26/139 (19%)
		EF1G	253..356	CDD:395522
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157345033
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740