DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstT1 and Clic4

DIOPT Version :9

Sequence 1:	NP_610509.2	Gene:	GstT1 / 35995	FlyBaseID:	FBgn0050000	Length:	228	Species:	Drosophila melanogaster
Sequence 2:	NP_114006.1	Gene:	Clic4 / 83718	RGDID:	61857	Length:	253	Species:	Rattus norvegicus

Alignment Length:	156	Identity:	34/156 - (21%)
Similarity:	56/156 - (35%)	Gaps:	63/156 - (40%)

- Green bases have known domain annotations that are detailed below.

  Fly    96 RVDEFLEWQHFNVRLVCSLFFRQVWLLPAKGLAPAPK-PES------------------------ 135
            :::||||      .::|          |.|.|..:|| |||
  Rat    90 KIEEFLE------EVLC----------PPKYLKLSPKHPESNTAGMDIFAKFSAYIKNSRPEANE 138

  Fly   136 ---------VKKLIKDVESNL-GLLERLWLE------KDFLVGDKLTVADIFGSSEINQMKLCQY 184
                     ::||.:.:.|.| |.::...:|      :.||.||::|:||.....:::.:|:...
  Rat   139 ALERGLLKTLQKLDEYLNSPLPGEIDENSMEDIKSSTRRFLDGDEMTLADCNLLPKLHIVKVVAK 203

  Fly   185 NVNEKQFPK--VAKWMERVRDATNPY 208
            .......||  ...|    |..||.|
  Rat   204 KYRNFDIPKGMTGIW----RYLTNAY 225

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstT1	NP_610509.2	GstA	5..204	CDD:223698	31/150 (21%)
		GST_N_Theta	5..80	CDD:239348
		GST_C_Theta	93..218	CDD:198292	34/156 (22%)
Clic4	NP_114006.1	Required for insertion into the membrane. /evidence=ECO:0000250	2..101		5/26 (19%)
		GST_N_CLIC	14..104	CDD:239359	6/29 (21%)
		O-ClC	17..252	CDD:129941	34/156 (22%)
		GST_C_family	111..251	CDD:295467	24/119 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166347838
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930