DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstT1 and clic2

DIOPT Version :9

Sequence 1:	NP_610509.2	Gene:	GstT1 / 35995	FlyBaseID:	FBgn0050000	Length:	228	Species:	Drosophila melanogaster
Sequence 2:	NP_001002561.2	Gene:	clic2 / 436834	ZFINID:	ZDB-GENE-040718-299	Length:	239	Species:	Danio rerio

Alignment Length:	144	Identity:	29/144 - (20%)
Similarity:	62/144 - (43%)	Gaps:	36/144 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    86 LYPKTLE-ERARVDEFLE-------WQHFNVRL---------VCSLFFRQVWLLPAKGLAPAPKP 133
            ||..||: :..:::||||       :.|.:.|.         :.:.|...:...|..........
Zfish    73 LYNGTLKTDFIKIEEFLETTLAPPRYPHLSPRYKESFDVGADIFAKFSAFIKNSPNNAFHEKALL 137

  Fly   134 ESVKKL-------IKD-VESNLGLLERLWLEKDFLVGDKLTVADIFGSSEINQMKL-----CQYN 185
            ...|:|       ::| ::.|:.:.:|     .||.|::||:||.....:::.:|:     |.::
Zfish   138 REFKRLDDYLNTPLQDELDQNISVSKR-----KFLDGNRLTLADCNLLPKLHVIKVAARKYCNFD 197

  Fly   186 VNEKQFPKVAKWME 199
            : ..||..|.::::
Zfish   198 I-PTQFTGVWRYLQ 210

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstT1	NP_610509.2	GstA	5..204	CDD:223698	29/144 (20%)
		GST_N_Theta	5..80	CDD:239348
		GST_C_Theta	93..218	CDD:198292	25/136 (18%)
clic2	NP_001002561.2	O-ClC	11..238	CDD:129941	29/144 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170589552
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930