DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstT1 and GstE4

DIOPT Version :9

Sequence 1:	NP_610509.2	Gene:	GstT1 / 35995	FlyBaseID:	FBgn0050000	Length:	228	Species:	Drosophila melanogaster
Sequence 2:	NP_611326.1	Gene:	GstE4 / 37109	FlyBaseID:	FBgn0063496	Length:	222	Species:	Drosophila melanogaster

Alignment Length:	238	Identity:	67/238 - (28%)
Similarity:	118/238 - (49%)	Gaps:	31/238 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSKAIKYYYDFLSQPSRALWIAMKLGKTPFEDCPVALRKQEQLTDEYRSINRFQKVPAIVDGKFQ 65
            |.|...|..| .|.|:||..:.:|....|||...|.|.::|..::::...|....||.:.|....
  Fly     1 MGKISLYGLD-ASPPTRACLLTLKALDLPFEFVFVNLFEKENFSEDFSKKNPQHTVPLLQDDDAC 64

  Fly    66 LGESVSIVRYLADKGVFSEQLYPKTLEERARVDEFLEWQHFNVRLVCS----------LFFRQVW 120
            :.:|.:|:.||.:|...|::||||.|.:||:||:.:   ||...::..          |||.:..
  Fly    65 IWDSHAIMAYLVEKYAPSDELYPKDLLQRAKVDQLM---HFESGVIFESALRRLTRPVLFFGEPT 126

  Fly   121 LLPAKGLAPAPKPESVKKLIKDVESNLGLLERLWLEKDFLVGDKLTVADIFGSSEINQMKLCQYN 185
            |       |..:.:.:.::...||:.|.       :.||:.||:||:||....|.|..:.:. ..
  Fly   127 L-------PRNQVDHILQVYDFVETFLD-------DHDFVAGDQLTIADFSIVSTITSIGVF-LE 176

  Fly   186 VNEKQFPKVAKWMERVRDATNPYYDEAHSFVYKTSQQAVKAKN 228
            ::..::||:|.|:||:::.  |||:||:........:.:::||
  Fly   177 LDPAKYPKIAAWLERLKEL--PYYEEANGKGAAQFVELLRSKN 217

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstT1	NP_610509.2	GstA	5..204	CDD:223698	58/208 (28%)
		GST_N_Theta	5..80	CDD:239348	21/74 (28%)
		GST_C_Theta	93..218	CDD:198292	35/134 (26%)
GstE4	NP_611326.1	GST_N_Delta_Epsilon	4..77	CDD:239343	21/73 (29%)
		GstA	6..196	CDD:223698	58/210 (28%)
		GST_C_Delta_Epsilon	91..209	CDD:198287	35/137 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45460099
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0625
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1231780at2759
OrthoFinder	1	1.000	-	-		FOG0000035
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100130
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X30
	7	6.650