DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment GstT1 and gst2

DIOPT Version :9

Sequence 1:	NP_610509.2	Gene:	GstT1 / 35995	FlyBaseID:	FBgn0050000	Length:	228	Species:	Drosophila melanogaster
Sequence 2:	NP_588517.1	Gene:	gst2 / 2539601	PomBaseID:	SPCC965.07c	Length:	230	Species:	Schizosaccharomyces pombe

Alignment Length:	240	Identity:	61/240 - (25%)
Similarity:	103/240 - (42%)	Gaps:	65/240 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 IAMKLGKTPFEDCPVALRKQEQLTDEYRSINRFQKVPAIVDGK---FQLGESVSIVRYLADKGVF 82
            :|:|.....:|......:|.||...|:.::|...:||.:||.|   :.:.||.:|:.|||||
pombe    20 LALKELNLSYEQIFYDFQKGEQKCKEHLALNPNGRVPTLVDHKNNDYTIWESDAILIYLADK--- 81

  Fly    83 SEQLYPKTLEERARVDEFLEWQHFNVRLVCSLFFRQ-----VWLLPAKGLA-------PAPKPES 135
                |.   .:|.....|.:.:::  :|:..|||:.     :|     |.|       ..|...:
pombe    82 ----YD---TDRKISLSFDDPEYY--KLIQYLFFQASGQGVIW-----GQAGWFNFFHHEPVVSA 132

  Fly   136 VKKLIKDVESNLGLLERLWLEKDFLVGDKLTVAD------------IFG------SSEINQMKLC 182
            |.:...:::..||:||.:..::|:||.:|.|:||            :||      ..|:.|:..
pombe   133 VTRYRNEIKRVLGVLEDILKDRDYLVANKYTIADLSFIPWNYNLGGLFGEGKFSFKEEVPQLDF- 196

  Fly   183 QYNVNEKQFPKVAKWMERVRDATNPYYDEAHSFVYKTSQQAVKAK 227
                 ||:|||...|.:|:.         |...|..|.::..|||
pombe   197 -----EKEFPKAYAWNQRLL---------ARPAVKATFEELAKAK 227

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstT1	NP_610509.2	GstA	5..204	CDD:223698	55/215 (26%)
		GST_N_Theta	5..80	CDD:239348	20/61 (33%)
		GST_C_Theta	93..218	CDD:198292	35/154 (23%)
gst2	NP_588517.1	GST_N_Ure2p_like	4..84	CDD:239346	22/73 (30%)
		GstA	5..226	CDD:223698	58/237 (24%)
		GST_C_Ure2p	96..219	CDD:198326	33/144 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000035
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100130
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X30
TreeFam	0	0.000	Not matched by this tool.
	5	4.710