DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstT1 and Gstt2

DIOPT Version :9

Sequence 1:	NP_610509.2	Gene:	GstT1 / 35995	FlyBaseID:	FBgn0050000	Length:	228	Species:	Drosophila melanogaster
Sequence 2:	XP_011241675.1	Gene:	Gstt2 / 14872	MGIID:	106188	Length:	251	Species:	Mus musculus

Alignment Length:	237	Identity:	76/237 - (32%)
Similarity:	114/237 - (48%)	Gaps:	26/237 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 IKYYYDFLSQPSRALWIAMKLGKTPFEDCPVALRKQEQLTDEYRSINRFQKVPAIVDGKFQLGES 69
            ::.|.|.|||||||::|..|....||:...|.:.|.:.:::::..:|...|||.:.||.|.|.||
Mouse     3 LELYLDLLSQPSRAVYIFAKKNGIPFQTRTVDILKGQHMSEQFSQVNCLNKVPVLKDGSFVLTES 67

  Fly    70 VS-------IVRYLADKGVFSEQLYPKTLEERARVDEFLEWQHFNVRLVCSLFFRQVWLLPAKGL 127
            .|       |:.||:.|...::..||..|:.||:|.|:|.|...|:|   ..|...:|......|
Mouse    68 PSSMIPSTAILIYLSSKYQVADHWYPADLQARAQVHEYLGWHADNIR---GTFGVLLWTKVLGPL 129

  Fly   128 APAPKPESVKKLIKDVESN-------LGLLERLWL-EKDFLVGDKLTVADIFGSSEINQMKLCQY 184
            .....|:      :.||.|       |..||..:| ::.||||.::|:||:....|:.|.....|
Mouse   130 IGVQVPQ------EKVERNRDRMVLVLQQLEDKFLRDRAFLVGQQVTLADLMSLEELMQPVALGY 188

  Fly   185 NVNEKQFPKVAKWMERVRDATN-PYYDEAHSFVYKTSQQAVK 225
            |:.|.: |::..|.|||..... ....||||.:.....||.|
Mouse   189 NLFEGR-PQLTAWRERVEAFLGAELCQEAHSTILSILGQAAK 229

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstT1	NP_610509.2	GstA	5..204	CDD:223698	69/213 (32%)
		GST_N_Theta	5..80	CDD:239348	29/81 (36%)
		GST_C_Theta	93..218	CDD:198292	40/133 (30%)
Gstt2	XP_011241675.1	GST_N_Theta	3..85	CDD:239348	29/81 (36%)
Gstt2	XP_011241675.1	GST_C_Theta	98..223	CDD:198292	40/134 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167844518
Domainoid	1	1.000	61	1.000	Domainoid score	I10389
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	148	1.000	Inparanoid score	I4379
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54888
OrthoDB	1	1.010	-	-		D1231780at2759
OrthoFinder	1	1.000	-	-		FOG0000035
OrthoInspector	1	1.000	-	-		mtm8775
orthoMCL	1	0.900	-	-		OOG6_100130
Panther	1	1.100	-	-	O	PTHR43917
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X30
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.770