DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1902 and TTPAL

DIOPT Version :9

Sequence 1:	NP_610507.1	Gene:	CG1902 / 35993	FlyBaseID:	FBgn0033434	Length:	312	Species:	Drosophila melanogaster
Sequence 2:	NP_001034288.1	Gene:	TTPAL / 79183	HGNCID:	16114	Length:	342	Species:	Homo sapiens

Alignment Length:	275	Identity:	72/275 - (26%)
Similarity:	124/275 - (45%)	Gaps:	15/275 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 SLEPELAEVARTQLCEDPSSTVAKIEALRTWIDKQI-YLEARTDDQFLVAFLRFCRWDVEEAKKR 69
            ||..:|...||.:|.|.|...:..::|||..:.|:. .|....||.||:.|||..::|.:.|.:.
Human    34 SLTEDLVTKAREELQEKPEWRLRDVQALRDMVRKEYPNLSTSLDDAFLLRFLRARKFDYDRALQL 98

  Fly    70 VLFYYTYKSKEREL---LKGRQVDDKLIELARSGIFATLPKPIGPGGPRIHYTRMGHIEPSKHSV 131
            ::.|::.:....|:   ||...:.|.|    .||....||. ..|.|..:...|.....||.:.:
Human    99 LVNYHSCRRSWPEVFNNLKPSALKDVL----ASGFLTVLPH-TDPRGCHVVCIRPDRWIPSNYPI 158

  Fly   132 SDIFRFHAFRAEIEINTDDNWNIAGVVEIIDFTKIPYSLLLQFDPGMFKRMNAFLEHGIPANLVA 196
            ::..|......|..|.:::. .:.|:|.:.|:..:..|....|.|.:.|::...|:.|.|..:.|
Human   159 TENIRAIYLTLEKLIQSEET-QVNGIVILADYKGVSLSKASHFGPFIAKKVIGILQDGFPIRIKA 222

  Fly   197 THIVNASRETQFVLGLVRNVMKQK--ELLHIH-STVASLRKAIGLEYLPVEMGGDNGSLSDAMTR 258
            .|:||..|..:.:..:::..:|:|  ....:| |.:.||...:....||.|.||..|.|..|  .
Human   223 VHVVNEPRIFKGIFAIIKPFLKEKIANRFFLHGSDLNSLHTNLPRSILPKEYGGTAGELDTA--T 285

  Fly   259 YETQLLSFSPYFTED 273
            :...||:....|.::
Human   286 WNAVLLASEDDFVKE 300

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1902	NP_610507.1	CRAL_TRIO_N	28..69	CDD:215024	14/41 (34%)
CG1902	NP_610507.1	CRAL_TRIO	100..248	CDD:279044	36/150 (24%)
TTPAL	NP_001034288.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..31
		CRAL_TRIO_N	56..102	CDD:215024	14/45 (31%)
		SEC14	121..277	CDD:238099	39/161 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1031056at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10174
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X106
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.920