DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1902 and Clvs1

DIOPT Version :9

Sequence 1:	NP_610507.1	Gene:	CG1902 / 35993	FlyBaseID:	FBgn0033434	Length:	312	Species:	Drosophila melanogaster
Sequence 2:	NP_001342112.1	Gene:	Clvs1 / 74438	MGIID:	1921688	Length:	354	Species:	Mus musculus

Alignment Length:	330	Identity:	80/330 - (24%)
Similarity:	136/330 - (41%)	Gaps:	51/330 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MAKIRSLE----PELAEVARTQLCEDPSSTVAKIEALRTWIDKQIYLE-ARTDDQFLVAFLRFCR 60
            :||:..|:    |:..|.||.:|.|:|......|:.:|..|..:..:. .||||.|::.|||..:
Mouse    20 LAKMTHLQAGLSPDTIEKARLELNENPDILHQDIQQVRDMIITRPDIGFLRTDDAFILRFLRARK 84

  Fly    61 WDVEEAKKRVLFYYTYKSKERELLKGRQVDDKLIELARSGIFATLPKPIGPG--GPRIHYTR--- 120
            :...:|.:.:..|:.|:....::.|..:.||..|:.|....|        ||  ..|.||.|
Mouse    85 FHQADAFRLLAQYFQYRQLNLDMFKNFKADDPGIKRALIDGF--------PGVLENRDHYGRKIL 141

  Fly   121 ---MGHIEPSKHSVSDIFRFHAFRAEIEINTDDNWNIAGVVEIIDFTKIPYSLLLQFDPGMFKRM 182
               ..:.:.|::|.:||.|......|:.|. |....|.|.:.|||::...:....:..|.:.|..
Mouse   142 LLFAANWDQSRNSFTDILRAILLSLEVLIE-DPELQINGFILIIDWSNFSFKQASKLTPSILKLA 205

  Fly   183 NAFLEHGIPANLVATHIVNASRETQFVLGLVRNVMKQK--ELLHIH-STVASLRKAIGLEYLPVE 244
            ...|:...||.....|.||.......:..|::..:|.|  :.:.:| :.:.||.:.|..|:||.|
Mouse   206 IEGLQDSFPARFGGVHFVNQPWYIHALYTLIKPFLKDKTRKRIFLHGNNLNSLHQLIHPEFLPSE 270

  Fly   245 MGG-----DNGSLSDAMTRYETQLLSFSPYFTEDERY------------GVDEKLREASEKDQER 292
            .||     |.|:.:..:         ..|.::::..|            ......||.|.|..:|
Mouse   271 FGGTLPPYDMGTWARTL---------LGPDYSDENDYTHTSYNAMHVKHTCSNLERECSPKPMKR 326

  Fly   293 GAPLV 297
            ...:|
Mouse   327 SQSVV 331

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1902	NP_610507.1	CRAL_TRIO_N	28..69	CDD:215024	12/41 (29%)
CG1902	NP_610507.1	CRAL_TRIO	100..248	CDD:279044	41/163 (25%)
Clvs1	NP_001342112.1	CRAL_TRIO_N	51..97	CDD:215024	12/45 (27%)
		CRAL_TRIO	125..274	CDD:366224	40/157 (25%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	317..354		6/15 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167835965
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D559280at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X106
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.750