DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1902 and Sec14l5

DIOPT Version :9

Sequence 1:	NP_610507.1	Gene:	CG1902 / 35993	FlyBaseID:	FBgn0033434	Length:	312	Species:	Drosophila melanogaster
Sequence 2:	NP_001121197.1	Gene:	Sec14l5 / 665119	MGIID:	3616084	Length:	696	Species:	Mus musculus

Alignment Length:	315	Identity:	60/315 - (19%)
Similarity:	120/315 - (38%)	Gaps:	57/315 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 LRTWIDKQIYLEARTDDQFLVAFLRFCRWDVEEAKKRVLFYYTYKSKERELLKGRQVDDKLIELA 97
            ||.|: ::.:......|:.::.|||...:.:::|:..:....:::       |..|| |.|::..
Mouse   249 LRHWL-QETHKGKIPKDEHILRFLRARDFHLDKARDMLCQSLSWR-------KQHQV-DLLLQTW 304

  Fly    98 RSGIFATLPKPIGP-----------GGPRIHYTRMGHIEPSKHSVSDIFRFHAFRAEIEINTDDN 151
            |.      |.|:..           .|..::..|:|.:: :|..:..:......:..:.:|.:..
Mouse   305 RP------PPPLQEFYAGGWHYQDIDGRPLYILRLGQMD-TKGLMKAVGEEALLQHVLSVNEEGQ 362

  Fly   152 WNIAGVVEIIDFTKIPYSLLLQFD---------PGM--FKRMNAFLEHGIPANLVATHIVNASRE 205
            ....|...........::.||..:         ||:  ..||...:|...|..|....||.|.|.
Mouse   363 KRCEGNTRQFGRPISSWTCLLDLEGLNMRHLWRPGVKALLRMIEVVEDNYPETLGRLLIVRAPRV 427

  Fly   206 TQFVLGLVRNVM----KQKELLHIHSTV---ASLRKAIGLEYLPVEMGGDNGSLSDAMTRYETQL 263
            ...:..||...:    ::|.|::..|..   ..|...:..:.:|..:||::     .....|..:
Mouse   428 FPVLWTLVSPFINENTRRKFLIYSGSNYQGPGGLVDYLDKDVIPDFLGGES-----VCNVPEGGM 487

  Fly   264 LSFSPYFTEDERYGVDEKLREASEKDQE----RGAP--LVTDVPNDGTFRMINFD 312
            :..|.|.||:|:...|: |::.||....    ||.|  :..::|...:....:||
Mouse   488 VPKSLYLTEEEQEQADQ-LQQWSETYHSASVLRGTPYEVAMEIPEGESVITWDFD 541

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1902	NP_610507.1	CRAL_TRIO_N	28..69	CDD:215024	8/35 (23%)
CG1902	NP_610507.1	CRAL_TRIO	100..248	CDD:279044	29/176 (16%)
Sec14l5	NP_001121197.1	PRELI	17..173	CDD:368069
		CRAL_TRIO_N	243..288	CDD:215024	8/39 (21%)
		SEC14	306..479	CDD:214706	30/184 (16%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900