Protein Alignment CG1827 and AGA

DIOPT Version :9

• Sequence 1: NP_610504.4
• Gene: CG1827 / 35989
• FlyBaseID: FBgn0033431
• Length: 393
• Species: Drosophila melanogaster
• Sequence 2: NP_000018.2
• Gene: AGA / 175
• HGNCID: 318
• Length: 346
• Species: Homo sapiens
• Alignment Length: 335
• Identity: 183/335 - (54%)
• Similarity: 226/335 - (67%)
• Gaps: 23/335 - (6%)

  Fly    56 LPMVINTWNFTAANVLAWRILKQSKGGLRQTRNAVVEGCSKCEKLQCDRTVGYGGSPDELGETTL 120
            ||:|:|||.|..|...|||.|  :.||  ...:||..||:.||:.|||.:||:||||||||||||
Human    27 LPLVVNTWPFKNATEAAWRAL--ASGG--SALDAVESGCAMCEREQCDGSVGFGGSPDELGETTL 87

  Fly   121 DAMVMDGATMDVGAVAGLRRIKDAIKVARHVLEHTQHTMLVGDAASAFANAMGFESESLVTPESK 185
            |||:|||.|||||||..|||||:||.|||.|||||.||:|||::|:.||.:|||.:|.|.|..|:
Human    88 DAMIMDGTTMDVGAVGDLRRIKNAIGVARKVLEHTTHTLLVGESATTFAQSMGFINEDLSTTASQ 152

  Fly   186 DMWLQWTAENCQPNFWKNVHPDPKVSCGPYKP-----RPTPLTRWKEDRARNEYEIGRKNHDTIG 245
            .:...|.|.|||||:|:||.|||...||||||     :..|:.:..||         .:.|||||
Human   153 ALHSDWLARNCQPNYWRNVIPDPSKYCGPYKPPGILKQDIPIHKETED---------DRGHDTIG 208

  Fly   246 MIAIDVESNIHAGTSTNGARHKIPGRVGDSPIPGAGAYADNEVGAAVATGDGDVMMRFLPSLLAV 310
            |:.|....:|.|||||||.:.||.||||||||||||||||:..|||.|||:||::||||||..||
Human   209 MVVIHKTGHIAAGTSTNGIKFKIHGRVGDSPIPGAGAYADDTAGAAAATGNGDILMRFLPSYQAV 273

  Fly   311 ETMRAGKPPAEAAQEGLRRILKHHKDFMGALIAVDRLGNYGAACYGLA---EFPFMVSSPAGADG 372
            |.||.|:.|..|.|:.:.||.||..:|.||:|..:..|:|||||..|:   :|.|||.: :..:.
Human   274 EYMRRGEDPTIACQKVISRIQKHFPEFFGAVICANVTGSYGAACNKLSTFTQFSFMVYN-SEKNQ 337

  Fly   373 PTRLETVKCI 382
            ||. |.|.||
Human   338 PTE-EKVDCI 346

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1827	NP_610504.4	Glycosylasparaginase	58..366	CDD:271335	175/315 (56%)
AGA	NP_000018.2	Glycosylasparaginase	29..332	CDD:271335	175/315 (56%)
		Substrate binding. /evidence=ECO:0000269|PubMed:8846222	234..237		2/2 (100%)
		Substrate binding. /evidence=ECO:0000269|PubMed:8846222	257..260		2/2 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165141711
Domainoid	1	1.000	318	1.000	Domainoid score	I1254
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H13
Inparanoid	1	1.050	340	1.000	Inparanoid score	I2371
Isobase	1	0.950	-	0	Normalized mean entropy	S3395
OMA	1	1.010	-	-		QHG58368
OrthoDB	1	1.010	-	-		D1487354at2759
OrthoFinder	1	1.000	-	-		FOG0004212
OrthoInspector	1	1.000	-	-		otm40941
orthoMCL	1	0.900	-	-		OOG6_105333
Panther	1	1.100	-	-	LDO	PTHR10188
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3475
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	14	13.860