Protein Alignment Smyd4-1 and smyd4

DIOPT Version :10

• Sequence 1: NP_610500.2
• Gene: Smyd4-1 / 35985
• FlyBaseID: FBgn0033427
• Length: 751
• Species: Drosophila melanogaster
• Sequence 2: XP_012812690.1
• Gene: smyd4 / 779741
• XenbaseID: XB-GENE-945037
• Length: 777
• Species: Xenopus tropicalis
• Alignment Length: 770
• Identity: 181/770 - (23%)
• Similarity: 292/770 - (37%)
• Gaps: 164/770 - (21%)

  Fly     1 MERLARTFSQQNELI--TLNENYKDEFETFKSLASMPADILQIFQKLALDLLQDLEQPVDRKGC- 62
            ||...:.:..|.:.|  .|..:.|::|.:.       ||:.:|||.....|.||.||.::|..|
 Frog    39 MEHPVQEWQDQAQSIWAHLTSSEKEKFSSI-------ADLDEIFQACLSHLQQDEEQLIERLCCN 96

  Fly    63 --AERSKN----LREEGNLMFKESASGSSKDSVLKACRLYSEAVFEAENAVEELSLAFANRGIAL 121
              ..:..|    .:||||..|.|....:       |..|||:|:..|::..|.|::.||||..||
 Frog    97 VTVAKDPNAVQFFKEEGNKRFAEKQYAT-------AAGLYSKAISHAKSGSEALAVCFANRSAAL 154

  Fly   122 QEYGYYREAYDDCSNALECGYPERLRHKVIMRQAFCAWKLKKIASLEEHLDYLGQLQLKESFEQQ 186
            ...|.|....:|..:|.:.|||||||:|::.|:|.|..:|:|.:|.:..|:.:..::.|:..:..
 Frog   155 FYLGQYSVCLEDIQHAQDHGYPERLRNKILQRKAECFQRLRKPSSCDPKLECVETVKPKKEPQTS 219

  Fly   187 LEDLKQKLELLKNQPREQETQGKVVDKSLGEILTDPGPRGRYMVAKEAISKGNVIFSER--ASCF 249
            .|.||:.  .|...|.       :.:.|....|.....:||:::|.:.|.:|.|:..|.  ||..
 Frog   220 TERLKEM--ALDRNPH-------ITNASCALHLNFDTRKGRHLLASQNIEQGEVLIWEEAFASVI 275

  Fly   250 VPLEQLL---------------ICQQCAATLMSAPIPCPNCHQRVVYCSRKCRE-AHSAIHKFEC 298
            :|..:..               .|..|...:: |.:||..| ....|||::|.: |..:.|..||
 Frog   276 IPERKQWRKEIKWDTRITACDHYCHYCLNRVI-ASLPCQYC-SFARYCSQECMDKAWRSYHYIEC 338

  Fly   299 AAYRKDILRLLGI-SHLALR-LLLTYIPYIRPHLQEMTSAK-------------------GMWEE 342
            :  ..|:|..||: .|.||| :|:.........|::..||.                   ..::.
 Frog   339 S--MGDLLLALGMFCHTALRAVLVAGCRLFSQSLEQTGSADATDKTKVCNSKNTYHEKYCSSYQS 401

  Fly   343 IMNLSRKPEESENAPEYLRSLRMVSQLDQAIDEELNYHILCANLLQLYLKEHTDFYDQFHSLPAS 407
            ::||....|......::|..|...:.          |..||..:.:..:...:...........:
 Frog   402 VVNLLPHTENHPAERKFLCGLTAAAL----------YKKLCLIMAKDLVSSTSQTEKSLTKESGT 456

  Fly   408 IEDWQLI---ISALILRFAGQLLANGHVGDALLGVGMEPKEFVMLQPELWQKPRHLKRGQLHNLS 469
            ||||..:   :...:||...||..|.....||                  |:........|...:
 Frog   457 IEDWSSVRQFLGPTVLRHMLQLYCNAQAVTAL------------------QENEDESSLSLVKSN 503

  Fly   470 HSDPITAINLPYLSLCNHACEPSIRTKFDGCSVVNYAAKDILEGEEIFNCY-----TMDYRNSLK 529
            .|..:.....|.|||.||:|:|:....|.|..|...|.:.|...||:.:||     .||.
 Frog   504 KSIRLATAVFPVLSLLNHSCDPNTTVSFTGRFVTVRANRPIRRDEEVTHCYGPHKLRMDV----- 563

  Fly   530 LQRSHPLKAIYKFECTCAKCTRTDPDQNYLSFHRYRCEKPNCRQEFLPDAKVQQNNLRWWLRCNA 594
            .:|...||..|.|.|.|..||.   :......|.:.|  |.|:.:.                 ..
 Frog   564 AERQQLLKDQYFFVCQCKACTE---ELKGKKTHGFFC--PLCKAQL-----------------EG 606

  Fly   595 EKPITCT------VCHELQHFAWYNEFLG---------LIGSSADSSKRQALFKAFDDLDKWLVD 644
            |:.:.||      ...:.|..:..|: ||         |..:..|::| ..|.....:.:.:|..
 Frog   607 EEALYCTGARCTYTASQTQLTSRLNQ-LGNHIQIAKVQLQDNKTDNAK-MTLMSCLSEAECFLSQ 669

  Fly   645 HHSLKRIMAEELVTACFYEIDGGTSLDEFEYEDLARIIRKQLEGIAAQCGDNSTE 699
            .|.|...:.:.|..|   |...|      .::..|..:||.:..:....|.:|.|
 Frog   670 DHLLLGEIMDHLAQA---EASDG------NWKAAAGHLRKSISIVKVHYGSSSME 715

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Smyd4-1	NP_610500.2	SET	217..>252	CDD:394802	10/36 (28%)
		zf-MYND	258..298	CDD:460312	12/40 (30%)
		SET	<359..549	CDD:394802	45/197 (23%)
smyd4	XP_012812690.1	TPR repeat	106..134	CDD:276809	11/34 (32%)
		TPR repeat	143..173	CDD:276809	11/29 (38%)
		SET_SMYD4	234..583	CDD:380934	86/385 (22%)
		zf-MYND	299..338	CDD:460312	12/40 (30%)