Protein Alignment Smyd4-1 and Lonrf3

DIOPT Version :9

• Sequence 1: NP_610500.2
• Gene: Smyd4-1 / 35985
• FlyBaseID: FBgn0033427
• Length: 751
• Species: Drosophila melanogaster
• Sequence 2: XP_006541467.1
• Gene: Lonrf3 / 74365
• MGIID: 1921615
• Length: 805
• Species: Mus musculus
• Alignment Length: 591
• Identity: 116/591 - (19%)
• Similarity: 179/591 - (30%)
• Gaps: 256/591 - (43%)

  Fly    65 RSKNLREEGNLMFKESASGSSKDSVLKACRLYSEAVFEAENAVEELSLAFANRGIALQEYGYYRE 129
            |:..||.|||.:|:|       ..|..|...|:|||..|.|.    .|.::||.   |.| :..|
Mouse   243 RASQLRHEGNRLFRE-------HQVEAALLKYNEAVRLAPND----HLLYSNRS---QIY-FTLE 292

  Fly   130 AYDDCSNALECGYPER-LRHKVIMRQAFCAWKLKKI-ASLEEHLDYL---GQLQLKESFEQQL-- 187
            :::|..:..|.....| :..|...|:|.....|.|: .:|:|.|..:   |:.:...|..|:|
Mouse   293 SHEDALHDAEIACKLRPMGFKAHFRKAQALATLGKVKEALKEFLYCVSLDGKNKSARSEAQRLLF 357

  Fly   188 ------------EDLKQKLELLKNQPREQE------TQG------KVVDKSLGEILTDPGPRGRY 228
                        |.....|:||...||.:|      |:|      |:..::| |:.......|.
Mouse   358 SFFSPSVPGESQEHSPDILKLLAPHPRLKEHVESMATEGTSHNLPKLSQENL-ELPHCSNQEGA- 420

  Fly   229 MVAKEAIS-----KGNVIFSE-------------------------RASCFV------------- 250
            ..|:|:.|     :|.|...|                         |..|.:
Mouse   421 AAAEESSSLANSAQGKVSSKEDRKKDQEGEDRDAASVRTGKCQEKKRNRCQIETQEDTELPNKVS 485

  Fly   251 ----PLEQ----------------LLICQQCAATLMSAPIPCPNCHQRVVYCSRKCREAHSAIHK 295
                |.||                .|.|..| ..|...|:..|..|...:.|..:|.:     |.
Mouse   486 KQDFPAEQGAKPDLSNPLGSFDASDLECSLC-MRLFYEPVTTPCGHTFCLKCLERCLD-----HN 544

  Fly   296 FECAAYRKDIL------RLLGISHLALRLLLTYIPYIRPHLQEMTSAKGMWEEIM----NLSRKP 350
            .:|... ||:|      |....:.:...|:.|::|      :|....|.::||.|    ||::
Mouse   545 AKCPLC-KDVLLQCLPSRKYSKNVILEELIATFLP------EEFKERKRLYEEEMEELSNLNK-- 600

  Fly   351 EESENAP-------------------------------------------------EY-----LR 361
                |.|                                                 ||     :|
Mouse   601 ----NVPIFVCTMAYPTVPCPLHIFEPCYRLMIRRCIETGTRQFGMCLGDPVKGFVEYGCILEIR 661

  Fly   362 SLRMVSQLDQAIDE--ELNYHIL-------------------------CANLLQLYLKEHTDFYD 399
            :::..|.....:|.  :..:.:|                         ||.|:.|    |...|:
Mouse   662 NVQFFSDGRSVVDSIGKRRFKVLHQGQRDGYNTADIEYIEDQKVQGDDCAELMGL----HNCVYE 722

  Fly   400 Q----FHSLPASIED---------------------------WQLIISALILRFAGQLLANGHVG 433
            |    ||||.||:::                           |.|.:..|..|.....||...:.
Mouse   723 QASSWFHSLKASLKNRILNHFGPMPEKDEDPQVNPNGPAWCWWTLAVLPLESRAQLPFLAMRSLK 787

  Fly   434 DALLGV 439
            |.|.|:
Mouse   788 DRLNGI 793

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Smyd4-1	NP_610500.2	zf-MYND	258..298	CDD:280009	9/39 (23%)
		SET	<447..526	CDD:214614
Lonrf3	XP_006541467.1	RING1-HC_LONFs	159..197	CDD:319427
		3a0801s09	<244..>359	CDD:273380	36/129 (28%)
		TPR repeat	244..272	CDD:276809	12/34 (35%)
		TPR repeat	277..307	CDD:276809	8/37 (22%)
		TPR repeat	312..335	CDD:276809	6/22 (27%)
		PEX10	<456..551	CDD:227861	16/101 (16%)
		RING2-HC_LONFs	510..551	CDD:319428	11/47 (23%)
		LON_substr_bdg	601..802	CDD:366967	30/197 (15%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910