back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Smyd4-1 and smyd2a

DIOPT Version :9

Sequence 1:	NP_610500.2	Gene:	Smyd4-1 / 35985	FlyBaseID:	FBgn0033427	Length:	751	Species:	Drosophila melanogaster
Sequence 2:	NP_001013568.1	Gene:	smyd2a / 541423	ZFINID:	ZDB-GENE-050320-126	Length:	435	Species:	Danio rerio

Alignment Length:	367	Identity:	78/367 - (21%)
Similarity:	130/367 - (35%)	Gaps:	129/367 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   217 EILTDPGPRGRYMVAKEAISKGNVIFSERASCFVPLEQLLICQ-----QCAATLMSAPIPCPNCH 276
            |....|| :||.:.|.:....|:::|:..|..:|    |.:.:     :|..|.......|..|.
Zfish    10 ERFLSPG-KGRGLKAIKHFKVGDLVFACPAYAYV----LTVNERGGRCECCFTRKEGLSKCGKCK 69

  Fly   277 QRVVYCSRKCREAHSAIHKFECAAY--------RKDILRLLGISHLALRLLLTYIPYIRPHLQEM 333
            | ..||:.:|:.....:||.||:|.        ..:.:||:.      |::|
Zfish    70 Q-AYYCNVECQRGDWPMHKLECSAMCAYGENWCPSETVRLVA------RIIL------------- 114

  Fly   334 TSAKGMWEEIMNLSRKPEESENAP-EYLRSLR-MVSQLDQAIDE--ELNYHILCANLLQLYLKEH 394
                          ::..::|..| |.:.:|| :.:.||:..:|  |:|...:.|  |..:...|
Zfish   115 --------------KQKHQTERTPSERVLTLRELEAHLDKLDNEKNEMNDTDIAA--LHHFYSRH 163

  Fly   395 TDFYDQFHSLPASIEDWQLIISALILRFAGQLLANG---------HVGDALLGVGMEPKEFVMLQ 450
            .||.|                :|.:.....|:..||         |:|.||
Zfish   164 LDFPD----------------NAALTELIAQVNCNGFTIEDEELSHLGSAL-------------- 198

  Fly   451 PELWQKPRHLKRGQLHNLSHSDPITAINLPYLSLCNHACEPSIRTKFDGCSVVNYAAKDILEGEE 515
                                        .|.::|.||:|.|::...:.|......|.::|...||
Zfish   199 ----------------------------FPDVALMNHSCSPNVIVTYKGTVAEVRAVQEINPEEE 235

  Fly   516 IFNCY-TMDYRNSLKLQRSHPLKAIYKFECTCAKCTRTDPDQ 556
            |||.| .:.|....:::|   ||..|.|.|.|.:||....|:
Zfish   236 IFNSYIDLLYPTEDRIER---LKDSYFFNCDCKECTSKSKDE 274

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.