DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Smyd4-1 and adhfe1

DIOPT Version :9

Sequence 1:	NP_610500.2	Gene:	Smyd4-1 / 35985	FlyBaseID:	FBgn0033427	Length:	751	Species:	Drosophila melanogaster
Sequence 2:	NP_989277.1	Gene:	adhfe1 / 394891	XenbaseID:	XB-GENE-966429	Length:	463	Species:	Xenopus tropicalis

Alignment Length:	256	Identity:	52/256 - (20%)
Similarity:	94/256 - (36%)	Gaps:	79/256 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   458 RHLKRGQLHNLSHSD-----PITAINLPY---LSLCNHACEPSIRTKFDGCSVVNYAAKDILEGE 514
            |.|:|......:||.     |:|.....|   :::.|.....:: |:..|..:.|..|:::
Frog    13 RQLQRASCKCPAHSHTYSQAPVTGRKTEYAFEMAVSNIRYGENV-TQEIGMDLQNLGARNV---- 72

  Fly   515 EIFNCYTMDYRNSLKLQRSHPLKAIYKFECTCAKCTRTDPDQNYLSFHRYRCEKPNCRQEFLPDA 579
                |...| ||.::|.   |:||:..   :..|        |.:||..|.      |....|..
Frog    73 ----CVMTD-RNLVELS---PVKAVLN---SLVK--------NNVSFKLYD------RVRVEPTD 112

  Fly   580 KVQQNNLRWWLRCNAEKPITCTVCHELQHFAWYNEFLGLIGSSA-DSSKRQALFKAFDDLDKWLV 643
            |...:.:.:     |:|             ..::.::|:.|.|. |:.|...|:.:....|  .:
Frog   113 KSFMDAIEF-----AKK-------------GQFDAYVGVGGGSVIDTCKAANLYSSSPGAD--FL 157

  Fly   644 DHHS------------LKRIMAEELVTACFYEIDGGTSLDEFEYEDLARIIRKQLEGIAAQ 692
            |:.:            ||.::|....:....|.   |.:..|:||:|     |...|||::
Frog   158 DYVNPPIGKGKAVTVPLKPLIAVPTTSGTGSET---TGIAIFDYEEL-----KAKTGIASR 210

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Smyd4-1	NP_610500.2	zf-MYND	258..298	CDD:280009
Smyd4-1	NP_610500.2	SET	<447..526	CDD:214614	15/75 (20%)
adhfe1	NP_989277.1	HOT	47..460	CDD:341469	44/222 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165168051
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930