Protein Alignment Smyd4-1 and SmydA-6

DIOPT Version :10

• Sequence 1: NP_610500.2
• Gene: Smyd4-1 / 35985
• FlyBaseID: FBgn0033427
• Length: 751
• Species: Drosophila melanogaster
• Sequence 2: NP_611182.1
• Gene: SmydA-6 / 36917
• FlyBaseID: FBgn0034183
• Length: 498
• Species: Drosophila melanogaster
• Alignment Length: 546
• Identity: 112/546 - (20%)
• Similarity: 195/546 - (35%)
• Gaps: 150/546 - (27%)

  Fly   226 GRYMVAKEAISKGNVIFSERASCFVPLEQLLICQQCAATLMSAPIPCPNCHQRVVYCSRKCREAH 290
            ||:.||...:..|..:..|.....:||.....|.:|.....|             :| ||||..
  Fly    21 GRFAVALCNVRAGETLLLENPIVVLPLMGERRCSKCFNLTES-------------FC-RKCRLL- 70

  Fly   291 SAIHKFECAAY-RKDILRLLGISHLALRLLLTYIPYIRPHLQEMTSAKGMWEEIMNLSRKPEESE 354
             |:.: :|:.: .:|..|                      |.||..:    ::.:.|.:|.|.:|
  Fly    71 -ALCE-DCSDHDERDCKR----------------------LAEMNFS----DDQVELLQKKEHTE 107

  Fly   355 NAP-----------EYLRSLRMVSQLDQAIDEELNYHILCANLLQLYLKEHTDFYDQFHSLPASI 408
            ..|           |.|.....:||:|.                ||..:..|:.:..:.....:.
  Fly   108 IQPVLKCLLLREHEETLPLYEEMSQMDS----------------QLMTRRGTEVWKNYQEHAFTP 156

  Fly   409 EDWQLIISALILRFAGQLLANGHVGDALLGVGMEPKEFVMLQPELWQKPRHLKRGQLHNLSHSDP 473
            .|:..:::.  ||.|    |:..:...|||: ::...:.:..||:....|.|.|
  Fly   157 LDYGGVLAQ--LRGA----ADEDLVQGLLGI-LDINAYEIRAPEVGGAMRGLYR----------- 203

  Fly   474 ITAINLPYLSLCNHACEPSIRTKFDGCSVVN-YAAKDILEGEEIFNCYTMDYRNSL--KLQRSHP 535
                   ...|..|:|.|::....|....:. ||.:.|..||.::||||    |.|  ..:|...
  Fly   204 -------RAGLFAHSCTPNLVISIDDEQRIKVYANRFIAAGEILYNCYT----NVLLGTEERRKI 257

  Fly   536 LKAIYKFECTCAKCTRTDPDQNYLSFHRYRCEKPNCRQEFL---PDAKVQQNNLRWWLRCNAEKP 597
            ||....|:|:|.:|  .||.:.......:.|.:.:|...::   ||..:      |....|.|
  Fly   258 LKVGKCFDCSCPRC--QDPTELGTHMSSFICSQCSCVDGYIVRQPDTGI------WQCLLNPE-- 312

  Fly   598 ITCTVCHELQHFAWYNEFLGLIGSSADSSKRQALFKAFDD----------LDKWLVDHHSLKRIM 652
                  |.|:     .||:    |:.....::.:|.|.||          |.:.|..:|.|...:
  Fly   313 ------HTLK-----QEFV----SNMLERAKEEIFHARDDIYRQELLLAKLSRLLHRNHFLMLDL 362

  Fly   653 AEELVTACFYEIDG-GTSLDEFEYEDLARIIRKQLEGIAAQCGDNSTEYIARM--TYLWDIIAQK 714
            .:.:.:.....:.. ||..::..||...|:.::.|..:..     .|..|:|:  ..|:: :|..
  Fly   363 KQNIASILRQILQNMGTRPNKKVYERKIRLCQEILLVLKV-----VTPGISRLKAIALYE-LANT 421

  Fly   715 KCRTDRKELLEMKGKVDYLASEHREV 740
            :....||...||:...:.|.:|...|
  Fly   422 QAELARKMYTEMEHSANDLLAELERV 447

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Smyd4-1	NP_610500.2	SET	217..>252	CDD:394802	6/25 (24%)
		zf-MYND	258..298	CDD:460312	9/39 (23%)
		SET	<359..549	CDD:394802	42/192 (22%)
SmydA-6	NP_611182.1	SET_SMYD	<185..271	CDD:380997	27/107 (25%)