Protein Alignment Smyd4-1 and SmydA-1

DIOPT Version :10

• Sequence 1: NP_610500.2
• Gene: Smyd4-1 / 35985
• FlyBaseID: FBgn0033427
• Length: 751
• Species: Drosophila melanogaster
• Sequence 2: NP_610944.1
• Gene: SmydA-1 / 36581
• FlyBaseID: FBgn0033917
• Length: 513
• Species: Drosophila melanogaster
• Alignment Length: 570
• Identity: 119/570 - (20%)
• Similarity: 193/570 - (33%)
• Gaps: 181/570 - (31%)

  Fly   272 CPNCHQRVVYCSRKCREAHSAIHKFECAAYRKDILRLLGISH---LALRLLLTYIPYIRPH---L 330
            |.||:| |.|||.:.::....:||..|..::        |:|   |...|:.|..  |:|:   |
  Fly    15 CSNCNQ-VSYCSVQHQKQDWKVHKPSCHPFK--------IAHNEQLGRHLVATRT--IKPYEIVL 68

  Fly   331 QEMTSAKGMWEEIMNLSRKPEESENAPEYLRSLRMVSQLD----------------QAIDE---- 375
            :|....:|           |.:. :||..|..|..:...|                :::||
  Fly    69 KEAPLVRG-----------PAQI-SAPVCLGCLNGIEAEDHIECEQCGWPLCGPECKSLDEHKAE 121

  Fly   376 ---------ELNY------HIL--CANLLQLYL--KEHTDFYDQFHSLPASIEDWQLIISALILR 421
                     ::|.      |.|  |.:.::..|  :..|:...:|..| .|:|..:        |
  Fly   122 CGLTKDRGQKVNVQEFGGPHPLYTCLSTVRCLLIGETSTEKASKFQDL-ESLESTR--------R 177

  Fly   422 FAGQLLANGHVGDALLGVGMEPKEFVMLQPELWQKPRHLKR------GQL----HNLSHSDPITA 476
            .:.|..|:      |:.:|    :|:   |:.::..:..:.      |.|    |.:..:||...
  Fly   178 GSNQWKAD------LVSIG----QFI---PKFFKTQKFTEEEIMKAVGALQINGHEVPTTDPSHV 229

  Fly   477 INLPYLSLCNHACEPSIRTKFD---GCSVVNYAAKDILEGEEIFNCYTMDYRNSLKLQRSHPLKA 538
            ......|...::|.|::...|:   .|  :.:|.::|.:...:..||:.....:...||.  |..
  Fly   230 AVFYTASFTENSCLPNLAKSFNKNGHC--ILWAPREIKKNAHLSICYSDAMWGTADRQRH--LMQ 290

  Fly   539 IYKFECTCAKCTR-TDPDQNYLSFHRYRCEKPNCRQEFLPDAKVQQNNLRWWLRCNAEKPITCTV 602
            ...|:|.|.:|.. |:.|.||.:.   :||...|....|| .|..:.|..|          .|..
  Fly   291 TKLFKCACERCVDVTELDTNYSAI---KCEDRQCGGLMLP-TKADEWNGSW----------RCRE 341

  Fly   603 CHELQHFAWYNEFLGLIGSSADSSKRQAL--FKAFDDLDKWLVDHH------------------- 646
            ||:.....:....|...|....|.::.|.  .|.....:|||...|
  Fly   342 CHKQVQKHYVERILERAGKDIQSMEKIAENGLKYLKHYEKWLPPQHFHMSEIKILLVQLLAKDQK 406

  Fly   647 ----------SLKRIMAEELVTACFYEIDGGTSLDEFEYEDLARIIRKQLEGIAAQCGDNSTEYI 701
                      .||...|.|||.  .||     .|...|...|..:..:....||.|     |..:
  Fly   407 ELMVIPDDRLLLKLNFARELVE--LYE-----KLTPCEVRTLGTLCFELHSAIAEQ-----TRRV 459

  Fly   702 ARMTYLWDIIAQKKCRTDRKELLEMKGKVDYLASEHREVFLNYYND-FIE 750
            |..|.|          :.:..|.|....||...:     :|.|.:| |||
  Fly   460 ALETSL----------SPKDRLEESLFYVDKCVN-----YLKYESDIFIE 494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Smyd4-1	NP_610500.2	SET	217..>252	CDD:394802
		zf-MYND	258..298	CDD:460312	10/25 (40%)
		SET	<359..549	CDD:394802	42/241 (17%)
SmydA-1	NP_610944.1	zf-MYND	4..40	CDD:460312	10/25 (40%)
		SET_SMYD	<217..301	CDD:380997	18/87 (21%)