Protein Alignment Smyd4-1 and Ehmt2

DIOPT Version :9

• Sequence 1: NP_610500.2
• Gene: Smyd4-1 / 35985
• FlyBaseID: FBgn0033427
• Length: 751
• Species: Drosophila melanogaster
• Sequence 2: XP_006256016.2
• Gene: Ehmt2 / 361798
• RGDID: 1302972
• Length: 1273
• Species: Rattus norvegicus
• Alignment Length: 544
• Identity: 101/544 - (18%)
• Similarity: 149/544 - (27%)
• Gaps: 231/544 - (42%)

  Fly    99 AVFEAENAVEELSLAFANRGIALQEYGYY---------REAYDDCSNA-LECGYPERLRHKVIMR 153
            |.|....|:.|:.|   |....|....|:         ||:|.||... |..|....||:|
  Rat   888 ASFTGSAAIAEVLL---NAQCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNK---- 945

  Fly   154 QAFCAWKLKKIASLEEHLDYLGQLQLKESFEQQLEDLKQKLELLKNQPREQETQGKVVDKSLGEI 218
            :...||.|     ..|..|....||           |.:||.|
  Rat   946 EGDTAWDL-----TPERSDVWFALQ-----------LNRKLRL---------------------- 972

  Fly   219 LTDPGPRGRYMVAKEAISKGN-VIFSERASCFVPLEQLLICQQCAATLMSAPIPCPN------CH 276
                             ..|| .:.:|:          :||:..|....:.||||.|      |.
  Rat   973 -----------------GVGNRAVRTEK----------IICRDVARGYENVPIPCVNGVDGEPCP 1010

  Fly   277 QRVVYCSRKCREA-----HSAIHKFECAA-------------------YRKDILRLLGISHLALR 317
            :...|.|..|..:     .:..|...|..                   |.||     |      |
  Rat  1011 EDYKYISENCETSTMNIDRNITHLQHCTCVDDCSSSNCLCGQLSIRCWYDKD-----G------R 1064

  Fly   318 LLLTYIPYIRPHLQEMTSAKGMWEEIMNLSRKPEESENAPEYLRSLRMVSQLDQAIDEELNYHIL 382
            ||..:.....|.:.|...|...|....|                         :.:...:...
  Rat  1065 LLQEFNKIEPPLIFECNQACSCWRSCKN-------------------------RVVQSGIKVR-- 1102

  Fly   383 CANLLQLYLKEHTDF-YDQFHSLPASIEDWQLIISALILRFAGQLLANGHVGDALLGVGMEPKEF 446
                ||||......: .....::|.         ...|..:.|:|     :.||...|..:.
  Rat  1103 ----LQLYRTAKMGWGVRALQTIPQ---------GTFICEYVGEL-----ISDAEADVREDD--- 1146

  Fly   447 VMLQPELWQKPRHLKRGQLHNLSHSD-PITAINLPYLS----LCNHACEPSI------------- 493
                            ..|.:|.:.| .:..|:..|..    ..||.|:|:|
  Rat  1147 ----------------SYLFDLDNKDGEVYCIDARYYGNISRFINHLCDPNIIPVRVFMLHQDLR 1195

  Fly   494 --RTKFDGCSVVNYAAKDILEGEEIFNCYTMDYRNSLKLQRSHPLKAIYKFECTCA--KCTRTDP 554
              |..|       ::::||..|||:    ..||.:     |...:|:.| |.|.|.  ||..:
  Rat  1196 FPRIAF-------FSSRDIRTGEEL----GFDYGD-----RFWDIKSKY-FTCQCGSEKCKHS-- 1241

  Fly   555 DQNYLSFHRYRCEKPNCRQEFLPD 578
             ...::..:.|..:.:...|.|||
  Rat  1242 -AEAIALEQSRLARLDPHPELLPD 1264

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Smyd4-1	NP_610500.2	zf-MYND	258..298	CDD:280009	12/50 (24%)
		SET	<447..526	CDD:214614	19/98 (19%)
Ehmt2	XP_006256016.2	PHA03247	<5..258	CDD:223021
		EHMT_ZBD	473..602	CDD:411018
		Ank_2	717..804	CDD:403870
		ANK repeat	749..778	CDD:293786
		Ank_2	785..878	CDD:403870
		ANK repeat	813..845	CDD:293786
		ANK repeat	848..878	CDD:293786
		Ank_2	852..944	CDD:403870	16/58 (28%)
		ANK repeat	880..911	CDD:293786	7/25 (28%)
		ANK repeat	913..944	CDD:293786	8/30 (27%)
		SET_EHMT2	1011..1249	CDD:380931	55/332 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910