Protein Alignment Smyd4-1 and SmydA-8

DIOPT Version :10

• Sequence 1: NP_610500.2
• Gene: Smyd4-1 / 35985
• FlyBaseID: FBgn0033427
• Length: 751
• Species: Drosophila melanogaster
• Sequence 2: XP_566389.3
• Gene: SmydA-8 / 3289599
• VectorBaseID: AGAMI1_001522
• Length: 522
• Species: Anopheles gambiae
• Alignment Length: 573
• Identity: 111/573 - (19%)
• Similarity: 193/573 - (33%)
• Gaps: 198/573 - (34%)

  Fly   215 LGEILTDPGP----------RGRYMVAKEAISKGNVIFSERASCFVPL---EQLLICQQCAATLM 266
            ||| |..||.          .||.:||...|:...::|.:|.....|.   .:::.|..|.:.|.
Mosquito    51 LGE-LVPPGEPPWDIATFEGYGRGLVATRDIAVNELVFVDRPVLVGPRVNNYEVIFCASCCSILR 114

  Fly   267 SAPIPCPNCHQRVVYCSRKC--REAHSAIHKFECAAYR----KDILRLLGISHLALRLLLTYIPY 325
            ...:....|  |:..||| |  ....|:.|..|||..:    ||..|                 |
Mosquito   115 RLQLCTGGC--RLPICSR-CDYSVGASSPHAAECALIQSWQPKDAGR-----------------Y 159

  Fly   326 IRPHLQEMTSAKGMWEEIMNLSRKPEESENAPEYLRSLRMVSQLDQAIDEELNYHILCANLLQLY 390
            .:..|..:||.:|.                         ::|:.|::|              .|.
Mosquito   160 SKNILYALTSIRGF-------------------------LLSERDRSI--------------VLQ 185

  Fly   391 LKEHTDFYDQFHSLPASIED---WQLIISALILRFAGQL--LANGHVGDALLGVGMEPKEFVMLQ 450
            ::.|....:....:...::|   |.|......:|:..|:  :.|.:..:....|..|...    |
Mosquito   186 MEGHPPRKEMTTEIERLLKDGYFWNLDGEGPAVRYLRQVVNILNTNAFETSRIVADEENN----Q 246

  Fly   451 PELWQKPRHLKRGQLHNLSHSDPITAINLPYLSLCNHACEPSIRTKFDG-CSVVNYAAKDILEGE 514
            .|:      :.|| |:.|.             :|.||.|.|::|..||| ..:..:|::.|.:||
Mosquito   247 HEI------ILRG-LYILG-------------ALMNHCCRPNVRYVFDGELRMRVHASRPIKKGE 291

  Fly   515 EIFNCYTMDYRNSLKLQRSHPLKAIY-----KFECTCAKCTRTDPDQ--NYLSFHRYRCEKPNCR 572
            :|.|.|:       |:......:.|:     .|.|.|.:|  .||.:  .||.  ..:|.:.:|
Mosquito   292 QIMNNYS-------KILWGSQHRIIHLCFSKNFLCCCDRC--KDPTEFGTYLG--ALKCVRESC- 344

  Fly   573 QEFLPDAKVQQNNLRWWLRCNAEKPITCTVCHELQHFAWYNEFLGLIGSSADSSKRQALFKAFDD 637
                |:.::...|           |:..:
Mosquito   345 ----PEGRLLPVN-----------PLKIS------------------------------------ 358

  Fly   638 LDKWLVDHHSLKRIMAEELVTACFYEIDGGTSLDEFEYEDLARIIRKQLEGIAAQCGDNSTEYIA 702
             ..|..|..|||   .:.:..:...||.....::        ..|:::...|.....|:..:::.
Mosquito   359 -SVWRCDRCSLK---MDNIKASKIQEIASRMIMN--------NAIKREASHIIDYLNDHIVKFLL 411

  Fly   703 ---RMTYLWDIIAQKKCRTDRKELLEMKGKVDYLASEHREVF--LNYYNDFIE 750
               :.|....:.|.||.::|| .|:|::.|..| ..|..::.  |||...|::
Mosquito   412 PTNQFTVELKLQAIKKIQSDR-PLVELREKEKY-CLEILDILQRLNYGECFVK 462

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Smyd4-1	NP_610500.2	SET	217..>252	CDD:394802	11/44 (25%)
		zf-MYND	258..298	CDD:460312	11/41 (27%)
		SET	<359..549	CDD:394802	40/200 (20%)
SmydA-8	XP_566389.3	SET_SMYD	<242..324	CDD:380997	28/112 (25%)