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Protein Alignment Smyd4-1 and Smyd2

DIOPT Version :9

Sequence 1:	NP_610500.2	Gene:	Smyd4-1 / 35985	FlyBaseID:	FBgn0033427	Length:	751	Species:	Drosophila melanogaster
Sequence 2:	NP_081072.1	Gene:	Smyd2 / 226830	MGIID:	1915889	Length:	433	Species:	Mus musculus

Alignment Length:	465	Identity:	92/465 - (19%)
Similarity:	168/465 - (36%)	Gaps:	150/465 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   225 RGRYMVAKEAISKGNVIFS-----------ERA----SCFVPLEQLLICQQCAATLMSAPIPCPN 274
            :||.:.|......|:::||           ||.    .||...|.|..|.:|
Mouse    17 KGRGLRALRPFHVGDLLFSCPAYACVLTVGERGHHCECCFARKEGLSKCGRC------------- 68

  Fly   275 CHQRVVYCSRKCREAHSAIHKFECAAYRKDILRLLGISHLALRLLLTYIPYIRPHLQEMTSAKGM 339
              ::..||..:|::....:||.||::     :.:||.:.             .|......:|:.:
Mouse    69 --KQAFYCDVECQKEDWPLHKLECSS-----MVVLGENW-------------NPSETVRLTARIL 113

  Fly   340 WEEIMNLSRKPEESENAPEYLRSLRMVSQLDQAIDEELNYHILCANLLQLYLKEHTDFYDQFHSL 404
            .::.::..|.|.|     :.|......|.||:..:|:       .:|:|..:.....||.::...
Mouse   114 AKQKIHPERTPSE-----KLLAVREFESHLDKLDNEK-------KDLIQSDIAALHQFYSKYLEF 166

  Fly   405 PASIEDWQLIISALILRFAGQLLANGHVGDALLGVGMEPKEFVMLQPELWQKPRHLKRGQLHNLS 469
            |..        |:|::.|| |:..||..        :|.:|                      ||
Mouse   167 PDH--------SSLVVLFA-QVNCNGFT--------IEDEE----------------------LS 192

  Fly   470 HSDPITAINLPYLSLCNHACEPSIRTKFDGCSVVNYAAKDILEGEEIFNCY------TMDYRNSL 528
            |   :.:...|.::|.||:|.|::...:.|......|.::|..|:|:|..|      |.|
Mouse   193 H---LGSAIFPDVALMNHSCCPNVIVTYKGTLAEVRAVQEIHPGDEVFTSYIDLLYPTED----- 249

  Fly   529 KLQRSHPLKAIYKFECTCAKCTRTDPDQNYLSFHRYRCEKPNCRQEFLPDAKVQQNNLRWWLRCN 593
               |:..|:..|.|.|.|.:||..|.|:..:...  :...|       |.|:..::.:|:
Mouse   250 ---RNDRLRDSYFFTCECRECTTKDKDKAKVEVR--KLSSP-------PQAEAIRDMVRY----- 297

  Fly   594 AEKPITCTVCHEL---QHFAWYNEFLGLIGSSADSSKRQALFKAFDDLDKWLVDHHSLKRIMAEE 655
                 ...|..|.   :|:...:|.|.:...|     ::.:...|:|.:.:::  |.:.:.|.
Mouse   298 -----ARNVIEEFRRAKHYKSPSELLEICELS-----QEKMSSVFEDSNVYML--HMMYQAMG-- 348

  Fly   656 LVTACFYEID 665
               .|.|..|
Mouse   349 ---VCLYMQD 355

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.