Protein Alignment Smyd4-1 and set-10

DIOPT Version :10

• Sequence 1: NP_610500.2
• Gene: Smyd4-1 / 35985
• FlyBaseID: FBgn0033427
• Length: 751
• Species: Drosophila melanogaster
• Sequence 2: NP_493620.2
• Gene: set-10 / 185237
• WormBaseID: WBGene00009370
• Length: 430
• Species: Caenorhabditis elegans
• Alignment Length: 543
• Identity: 96/543 - (17%)
• Similarity: 174/543 - (32%)
• Gaps: 203/543 - (37%)

  Fly   228 YMVAKE----AISKGNVIFSER--ASCFVPLE-----QLLICQQCAATLMSAPIPCPNCHQRVVY 281
            |.||:|    |:....  |||.  |:||:.::     ::|.|..|.|               |.|
 Worm     2 YTVAREQPLAAVLSPQ--FSELYCATCFLEIDSSQETEILTCDDCLA---------------VSY 49

  Fly   282 CSRKC-REAHSAIHKFECAAYRKDILRLLGIS-------HLALRLLL----TYIPYIRPHLQEMT 334
            |:.|| |:...:.|:|||     :|||..|.|       .|.:|:||    |..|.....:.|
 Worm    50 CTLKCQRKDWKSCHQFEC-----EILRCQGSSTPMTLTMKLCIRVLLASRSTQTPSFNGAVLE-- 107

  Fly   335 SAKGMWEEIMNLSRKPEESENAPEYLRSLRMVSQLDQAIDEELNYHILCANLLQLYLKEHTDFYD 399
                      :|....:|..::||:.:.|..|..:..:..:.:
 Worm   108 ----------DLETNYKEFRSSPEHNQFLSDVLTIISSSGQNI---------------------- 140

  Fly   400 QFHSLPASIEDWQ---LIISALILRFAGQLLANGHVGDALLGVGMEPKEFVMLQPELWQKPRHLK 461
                .|.|:|..:   :|.|.|...|:
 Worm   141 ----FPTSLETNKTIGIICSVLCNSFS-------------------------------------- 163

  Fly   462 RGQLHNLSHSDPITAINLPYLSLCNHACEPSIRTKFDGCSVVNYAAKDILEGEEIFNCYTMDYRN 526
               :.|....:||.:.....::..||:|..:....|:|..|.....:     ||.....|:.|.:
 Worm   164 ---IINEKRVEPIGSGLYVGVAKHNHSCASTSHVVFEGNQVFLRTNQ-----EEYSKELTISYVS 220

  Fly   527 SL--KLQRSHPLKAIYKFECTCAKCTRTDPDQNYLSFHRYRCEKPNCRQEFLPDAKVQQNNLRWW 589
            .:  ..:|...::.::...|.|..|...:.|...||   .:|...|| ..|:..:.
 Worm   221 RMLPTSERRKTIRGVHFLTCQCEMCKNEELDLIGLS---SKCRTKNC-TGFVKGSG--------- 272

  Fly   590 LRCNAEKPITCTVCHELQHFAWYNEFLGLIGSSADSSKRQALFKAFDDLDKWLVDHHSLKRIMAE 654
                     .|:||.:|....:                .|::....:.||            :.|
 Worm   273 ---------NCSVCEKLAFLPF----------------EQSIHSTLNLLD------------IIE 300

  Fly   655 ELVTACFYEIDGGTSLDEFEYEDLARIIRKQLEGIAAQCGDNSTEYIARMTYLWDIIAQKKCRTD 719
            .|     ::.:..|::.|..|   .:.:|...:.|.|:|.....:...::.|         |.:.
 Worm   301 NL-----HKTNQFTTVQELAY---LQKLRADYQDILAECNVAILQLDEQIAY---------CSSS 348

  Fly   720 RKELLEMKGKVDYLASEHREVFL 742
            .:.:.::  .:|.:|....|.|:
 Worm   349 LENVNDL--DLDLIAGRGSEHFI 369

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Smyd4-1	NP_610500.2	SET	217..>252	CDD:394802	11/29 (38%)
		zf-MYND	258..298	CDD:460312	11/40 (28%)
		SET	<359..549	CDD:394802	25/194 (13%)
set-10	NP_493620.2	zf-MYND	23..67	CDD:460312	15/58 (26%)
		SET	57..247	CDD:394802	46/278 (17%)