Protein Alignment Smyd4-1 and AgaP_AGAP005253

DIOPT Version :9

• Sequence 1: NP_610500.2
• Gene: Smyd4-1 / 35985
• FlyBaseID: FBgn0033427
• Length: 751
• Species: Drosophila melanogaster
• Sequence 2: XP_001688544.1
• Gene: AgaP_AGAP005253 / 1274967
• VectorBaseID: AGAP005253
• Length: 638
• Species: Anopheles gambiae
• Alignment Length: 649
• Identity: 135/649 - (20%)
• Similarity: 233/649 - (35%)
• Gaps: 203/649 - (31%)

  Fly    29 KSLASMPADILQIFQKLALDLL-QDLEQPV----DRKGCAE----------RSKNLREEGNLMFK 78
            :||.....:::::|.:|..:|| |.:.:.|    |:...||          |:...|:..||  .
Mosquito     3 ESLQEKECNVVKLFHELWEELLKQRINELVHNQRDKDKVAEIIKREIEDFLRTFPFRDRFNL--H 65

  Fly    79 ESASGSSKDSVLKAC----------------RLYSEAVFEAENAVEELSLAFANRGIALQEYGYY 127
            ..|..::|....:.|                :.|:|::..:|...|..:||:.||.....::|.|
Mosquito    66 PDAKDNAKALAARNCGNERFAPSIGEYMESLQHYNESIAYSEQGSETRALAYGNRSAVCLKFGLY 130

  Fly   128 REAYDDCSNALECGYPERLRHKVIMRQAFCAWKLKKIASLEEHLDYLGQLQLKESFEQQLEDLKQ 192
            .|..::...|....||.:|..|:..|:.:                      :|...|:..|:...
Mosquito   131 EECLENIRLARASNYPMQLADKLNKREQY----------------------VKRCIEEDAEEFSD 173

  Fly   193 KLELLKNQPREQETQGKVVDKSLGEILTDPGPR------------------------GRYMVAKE 233
            |:         ..|.|:...::.|.    |.|:                        ||::|..:
Mosquito   174 KV---------MHTPGQYRPRNSGY----PAPKLSYEAHANVPQLVKCVELRQNSEFGRHLVTTQ 225

  Fly   234 AISKGNVIFSER--ASCFVPLEQLLICQQCAATLMSAPIPCPNCHQRVVYCSRKCRE-AHSAIHK 295
            .:..|:|:..|:  ||.....|:...|..|........|||..| ...:|||.:|.: |:...|:
Mosquito   226 HLKAGDVLLIEKPYASMLNDKERYKRCAFCHNEDTFTLIPCEGC-TLTMYCSDECMDKAYKQYHR 289

  Fly   296 FECAAYRKDILRLLGI---SHLALRLLLTYIPYIRPHLQEMTSAKGMWEEIMNLSRKPEESENAP 357
            :||...| |..|:.|.   ..:.||::.|.|......|:..|:         :|:...|...||
Mosquito   290 YECGVLR-DCWRIAGRLVGGIVGLRMVATAIASFEQDLEGWTN---------HLNALDETKVNA- 343

  Fly   358 EYLRSLRMVSQLDQAIDEEL--NYHILCAN-----------------LLQLYLKEHTDFYDQFHS 403
                   .....::..|.::  ..|:|..|                 ::...|.|.||......|
Mosquito   344 -------FTVDWNKVTDSDIYDTVHVLATNQKRRSREDLAVLMFFTSIVHRLLLERTDLGPFCES 401

  Fly   404 LPASIEDWQLIISALILRFAGQLLANGHVGDALLGVGMEPKEFVMLQPELWQKPRHLKRGQL--- 465
            .|...:    ::..|:||.....|.|              |:.|.          |::|.:.
Mosquito   402 SPTRSK----LLFDLLLRHWQTSLIN--------------KKQVY----------HVQRSECQDE 438

  Fly   466 ------HNLS---------HSDPITAINL-PYLSLCNHACEPSIRT--KFDG-CSVVNYAAKDIL 511
                  :|.:         :||.:.||.: |..|:.||:|.|::..  ..|| |:.|  |.:.|.
Mosquito   439 EDEYYEYNYAGYDSDDEEEYSDEMHAIAVYPLFSMVNHSCIPNVAPIHLLDGRCAFV--ATRPIA 501

  Fly   512 EGEEIFNCY---TMDYRNSLKLQRSHPLKAIYKFECTCAKC---------TRTDPDQNYLSFHR 563
            .||::|:.|   :||:..|.::   ..|:..|.|:|.||.|         ..|..:.|:|...|
Mosquito   502 AGEQLFDVYAFASMDFDRSFRI---FCLRKSYYFKCRCAVCESFSYVDVRNMTPRETNFLRLLR 562

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Smyd4-1	NP_610500.2	zf-MYND	258..298	CDD:280009	12/40 (30%)
		SET	<447..526	CDD:214614	26/103 (25%)
AgaP_AGAP005253	XP_001688544.1	TPR_11	73..142	CDD:290150	14/68 (21%)
		zf-MYND	252..292	CDD:280009	12/40 (30%)
		SET	<472..507	CDD:279228	13/36 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1278034at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920