Protein Alignment Smyd4-1 and Smyd4-2

DIOPT Version :10

• Sequence 1: NP_610500.2
• Gene: Smyd4-1 / 35985
• FlyBaseID: FBgn0033427
• Length: 751
• Species: Drosophila melanogaster
• Sequence 2: XP_061519376.1
• Gene: Smyd4-2 / 1272955
• VectorBaseID: AGAMI1_014187
• Length: 669
• Species: Anopheles gambiae
• Alignment Length: 657
• Identity: 157/657 - (23%)
• Similarity: 245/657 - (37%)
• Gaps: 180/657 - (27%)

  Fly    18 NENYKDEFETFKSLASMPADILQ-IFQKLALD------LLQD----------LE--QPVDRKGCA 63
            ||.|:...|.|   ....|..|| ::||:..|      :.:|          ||  :||.|...|
Mosquito    28 NEFYQSVAENF---TGKSARWLQDVYQKVPSDKERLRLIYEDPVVAYEVQGTLEHVEPVFRGKDA 89

  Fly    64 ERSKNLREEGNLMFKESASGSSKDSVLKACRLYSEAVFEA-----ENAVEE---LSLAFANRGIA 120
            :.|...||:...:..|:   ..:.:::.||    :||..|     :..:::   |:||...|...
Mosquito    90 KFSWQRREQALKLLGEN---KLQQALIIAC----QAVMRAPGQGVDRYIDKGLTLALALWTRAEV 147

  Fly   121 LQEYGYYREAYDDCSNALECGYPERLRHKVIMRQAFC------------AWKLKKIASLEEHLDY 173
            .......:.|..|...|.:||.|.:.......|.|.|            |.||  ...|..|.:|
Mosquito   148 FIRQLDGKRALQDLQLAAKCGLPVKQNADYYARVAKCYALIGENGRAEVAAKL--FHQLSGHNNY 210

  Fly   174 -LGQLQLKESFEQQLEDLKQKLELLKNQPREQETQGKVVDKSL---------GEIL--------- 219
             ||:||      :.||||:    :||     |||....|::||         ||||
Mosquito   211 ALGRLQ------EDLEDLR----VLK-----QETPSVEVERSLPKLAGEGENGEILGASSKIKLA 260

  Fly   220 -TDPGPRGRYMVAKEAISKGNVIFSE--RASCFVPLEQLLICQQCAATLMSAPIPCPNCHQRVVY 281
             :...|||||:||...:..|.||.:|  .|:|.........|..|.:.|: ||:.||:| ..|.:
Mosquito   261 GSKEDPRGRYVVAAADLGPGEVILTEPAYAACLHAKYYGTHCSACFSRLI-APVACPDC-CGVAF 323

  Fly   282 CSRKCRE-AHSAIHKFECAAYRKDILRLLGIS---HLALRLLLTYIPYIRPHLQEMTSAKGMWEE 342
            ||..||: |.:..|:|||...  |::...|:|   |:|||               |.:..|..|:
Mosquito   324 CSVACRDKACATYHRFECQYL--DLMIGSGMSILCHVALR---------------MVTQAGTPEK 371

  Fly   343 IMNLSRKPEESENAPEYLRSLRMVSQLDQAIDEELNYHILCANLLQLYLKEHTDFYDQFHSLPAS 407
            ::      ||.    :.||.........:..::.....::.|.||:...|  .:|:.:..:....
Mosquito   372 VL------EEG----KMLRDTFCAHTEHRDPEDHFKRTLMTAFLLRCLQK--AEFFGRRTTEAPE 424

  Fly   408 IEDWQLIISALILRFAGQLLANGH-------VGD--------ALLGVGMEPKEFVMLQPELWQKP 457
            ..:.:|.:.|::|.....|..|.|       .|:        ..:|||
Mosquito   425 PTEQELEVGAVLLSALQSLQFNAHEVYETRITGEHRFDTAKVQYIGVG----------------- 472

  Fly   458 RHLKRGQLHNLSHSDPITAINLPYLSLCNHACEPSIRTKFDGCSVVNYAAKDILEGEEIFNCYTM 522
              :.||                  .|:.||.|.|.:...|.|.:::.:.::.|..|..:...|..
Mosquito   473 --IYRG------------------ASMFNHECYPGVTRTFLGTAMILHTSRPIPAGAVVPENYGP 517

  Fly   523 DYRNSLKLQRSHPLKAIYKFECTCAKCTRTDPDQNYL-SFHRYRCEKPNCRQEFLPDAKVQQNNL 586
            .:....|..|...|::.|.|:|.|..|....|..:.| :..|.||....|.......:|..|.|
Mosquito   518 HFMRQPKAIRQRNLRSRYWFKCDCRACAEDWPQMDKLPAKPRLRCPTEGCGNALAYPSKPSQRN- 581

  Fly   587 RWWLRCN 593
               .:||
Mosquito   582 ---AKCN 585

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Smyd4-1	NP_610500.2	SET	217..>252	CDD:394802	16/46 (35%)
		zf-MYND	258..298	CDD:460312	16/40 (40%)
		SET	<359..549	CDD:394802	36/204 (18%)
Smyd4-2	XP_061519376.1	None