Protein Alignment Smyd4-1 and AgaP_AGAP011267

DIOPT Version :9

• Sequence 1: NP_610500.2
• Gene: Smyd4-1 / 35985
• FlyBaseID: FBgn0033427
• Length: 751
• Species: Drosophila melanogaster
• Sequence 2: XP_309378.2
• Gene: AgaP_AGAP011267 / 1270662
• VectorBaseID: AGAP011267
• Length: 540
• Species: Anopheles gambiae
• Alignment Length: 659
• Identity: 144/659 - (21%)
• Similarity: 253/659 - (38%)
• Gaps: 175/659 - (26%)

  Fly    47 LDLLQDLEQPVDRKGCAERSKNLREEGNLMFKESASGSSKDSVLKACRLYSEAVFEAENAVEELS 111
            |:|..|::...       ::..||.|||.||..:..     ..::|.:||:|::..:|....|.:
Mosquito     3 LNLRNDVKDKA-------KADQLRSEGNKMFHPNVK-----RYIEAIKLYNESIAFSEKGSTERA 55

  Fly   112 LAFANRG-IALQEYGYYREAYDDCSN----ALECGYP-ERL--RHKVIMRQAFCAWKLKKIASLE 168
            ||:|||. |.|.     .:.::||..    |.|..|| |:|  |.|. .:.|....:.|..:|.:
Mosquito    56 LAYANRSTICLT-----MQRFEDCLENIRLARESNYPGEKLNQREKE-AKTALTKARNKNASSSK 114

  Fly   169 EHLDYLGQLQLKESFEQQLEDLKQKLELLKNQPREQETQGKVVDKSLGEILTDPGPRGRYMVAKE 233
            ...|.:.:.:|....::....:...|||.||:                       ..||::|...
Mosquito   115 ISPDVVEEPELSYPSKENAPQVANCLELRKNE-----------------------EYGRHVVTTR 156

  Fly   234 AISKGNVIFSERASCFVPLEQL--LICQQCAATLMSAPIPCPNCHQRVVYCSRKC-REAHSAIHK 295
            .:..|:|:..||....|..:.|  :.|..|........|||..| ...:|||.:| .:|::..|:
Mosquito   157 KLKVGDVVMIERPFVTVLRDSLRYVRCDFCHEERPFTLIPCEGC-TAAMYCSEECLSKAYNKYHR 220

  Fly   296 FECAAYRK-----DILRLLGISHLALRLLLTY---IPYIRPHLQEMTSA----------KGMWEE 342
            :||...|.     |.|.|:.|..:|: .:.|:   ...::.||..:..:          |...::
Mosquito   221 YECGLLRDMVEVFDELPLIAIRMIAI-AITTFDNNPEALKDHLDVLDESNVNGFTMDWNKATQQD 284

  Fly   343 IMNLSRKPEESENAPEYLRSLRMVSQLDQAIDEE-LNYHILCANLLQLYLKEHTDFYDQFHSLPA 406
            |.|                ::.:::...:..|.. |.:||..|.:|...:.|.|:......:.||
Mosquito   285 IFN----------------TVHVLTTNQERRDSNFLAFHIFNATILHTLVLERTELGPVCEANPA 333

  Fly   407 SIEDWQLIISALILRFAGQLLANGHVGDALLGVGMEPKEF--VMLQPELWQKPRHLKRGQLHNLS 469
            :    ...:..||||:                  |:..||  .:|....::..:::
Mosquito   334 T----NKFLLDLILRY------------------MQIVEFNRKLLSSNAYKVKKYV--------- 367

  Fly   470 HSDPITAINLPYLSLCNHACEPSIR--TKFDG-CSVVNYAAKDILEGEEIFNCYTMDYRNSLKLQ 531
             ::.:.....|.:|:.||:|.|:::  |..|| |:|  :..:.:|||.::|:.|..|:::..:..
Mosquito   368 -AESLATSCYPLISMLNHSCAPNVQRITLRDGRCAV--FVIRPVLEGSQLFDSYETDHKSHERAM 429

  Fly   532 RSHPLKAIYKFECTCAKCTRTDPDQNYLSFHRYRCEKPNCRQEFLPDAKVQQNNLRWWLRCNAEK 596
            |...|...|.|.|||..||...|....|                |..:.|          .|:|
Mosquito   430 RQLMLSFTYSFRCTCEACTFNYPTLKVL----------------LEGSDV----------TNSE- 467

  Fly   597 PITCTVCHELQHFAWYNEFLGLIGSSADSSKRQALFKAFDDLDKWLVDHHSLKRIMAEELVTACF 661
                    ::....:||...    ||.|..|   :.|...:|..:|   :...::..|..|  ||
Mosquito   468 --------DMAKHLYYNRMF----SSHDDKK---VRKIMAELRSFL---NETPKLYPESQV--CF 512

  Fly   662 YEIDGGTSL 670
            .::|...||
Mosquito   513 RQVDFVRSL 521

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Smyd4-1	NP_610500.2	zf-MYND	258..298	CDD:280009	12/40 (30%)
		SET	<447..526	CDD:214614	18/81 (22%)
AgaP_AGAP011267	XP_309378.2	TPR_11	14..83	CDD:290150	23/78 (29%)
		zf-MYND	183..223	CDD:280009	12/40 (30%)
		SET	<362..418	CDD:279228	15/67 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2084
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1278034at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820