DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Smyd4-1 and AgaP_AGAP011270

DIOPT Version :9

Sequence 1:	NP_610500.2	Gene:	Smyd4-1 / 35985	FlyBaseID:	FBgn0033427	Length:	751	Species:	Drosophila melanogaster
Sequence 2:	XP_309376.4	Gene:	AgaP_AGAP011270 / 1270660	VectorBaseID:	AGAP011270	Length:	341	Species:	Anopheles gambiae

Alignment Length:	358	Identity:	73/358 - (20%)
Similarity:	144/358 - (40%)	Gaps:	71/358 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    90 LKACRLYSEAVFEAENAVEELSLAFANRGIALQEYGYYREAYDDCSNALECGYP-ERL--RHKVI 151
            ::|.:||:|::..:|....|.:||:.||.....:...:.|..::...|.|..|| |:|  |.|.:
Mosquito    21 IQAIKLYNESIAFSEKGSTERALAYVNRSNICLKMQRFEECLENIRLARESNYPGEKLIQREKEV 85

  Fly   152 MRQAFCAWKLKKIASLEEHLDYLGQLQLKESFEQQLEDLKQKLELLKNQPREQETQGKVVDKSLG 216
             :.|....:.|..:|.:...|.:.:.:|..:.::....:...|||.||:
Mosquito    86 -KNALAKARNKNASSSKASPDVVEEPELSYAAKENAPQVANCLELRKNE---------------- 133

  Fly   217 EILTDPGPRGRYMVAKEAISKGNVIFSERASCFVPLE--QLLICQQCAATLMSAPIPCPNCHQRV 279
                   ..||::|....:..|:|:..||....|..:  :.:.|..|........|||..| ...
Mosquito   134 -------EYGRHVVTTRKLKVGDVVMIERPFVTVLKDSFRYVRCDFCHEERPFTLIPCEGC-TMA 190

  Fly   280 VYCSRKC-REAHSAIHKFECAAYRKDILRLL-GISHLALRLLLTYI-------PYIRPHLQEMTS 335
            :|||.:| .:|::..|::||...| |:..:. .:..:|:|::...|       ..::.||..:..
Mosquito   191 MYCSEECLSKAYNNYHRYECGLLR-DLWEVFEAVPLIAIRMIAIAIATFDNNPEALKDHLDALDE 254

  Fly   336 A----------KGMWEEIMNLSRKPEESENAPEYLRSLRMVSQLDQAIDE-ELNYHILCANLLQL 389
            :          |...::|.|                ::.:::...:..|. .:.::|..|.:|..
Mosquito   255 SNVNGFTMDWNKATQQDIFN----------------TVHVLTTNQERRDSFFVAFYIFNATILHT 303

  Fly   390 YLKEHTDFYDQFHSLPASIEDWQLIISALILRF 422
            .:.|.|:......:.||:    ...:..||||:
Mosquito   304 LVLERTELEPVCEANPAT----NKFLLDLILRY 332

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Smyd4-1	NP_610500.2	zf-MYND	258..298	CDD:280009	12/40 (30%)
Smyd4-1	NP_610500.2	SET	<447..526	CDD:214614
AgaP_AGAP011270	XP_309376.4	TPR_11	<18..70	CDD:290150	12/48 (25%)
		TPR repeat	41..71	CDD:276809	6/29 (21%)
		zf-MYND	170..210	CDD:280009	12/40 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2084
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D30377at6960
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820