Protein Alignment Smyd4-1 and smyd1

DIOPT Version :10

• Sequence 1: NP_610500.2
• Gene: Smyd4-1 / 35985
• FlyBaseID: FBgn0033427
• Length: 751
• Species: Drosophila melanogaster
• Sequence 2: XP_012811600.1
• Gene: smyd1 / 100145429
• XenbaseID: XB-GENE-978314
• Length: 491
• Species: Xenopus tropicalis
• Alignment Length: 514
• Identity: 107/514 - (20%)
• Similarity: 171/514 - (33%)
• Gaps: 220/514 - (42%)

  Fly   217 EILTDPGPRGRYMVAKEAISKGNVIFSERA---------------SCFVPLEQLLICQQCAATLM 266
            ||....| :||.:.|......|::||:|.|               |||...|:||.|.||..
 Frog     5 EIFESEG-KGRGLRAIRESWAGDIIFAEPAYSAVVFDNLSHSVCHSCFKRQEKLLRCGQCKF--- 65

  Fly   267 SAPIPCPNCHQRVVYCSRKCREAHSAIHKFECAAYRK------DILRLLGISHLALRLLLTYIPY 325
                    .|    ||.|.|::...|.||.||.|.:|      :.:||
 Frog    66 --------AH----YCDRTCQKESWANHKNECVAIKKAGKAPNENIRL----------------- 101

  Fly   326 IRPHLQEMTSAKGMWEEIMNLSRKPEESENAPEYLRSLRMVSQLDQAIDEELNYHILCANLLQLY 390
                     :|:.:|       |...|.....|..    :||     ||:
 Frog   102 ---------AARILW-------RIEREGSGLTEGC----LVS-----IDD--------------- 126

  Fly   391 LKEHTDFYDQFHSLPASIEDWQLIISALILRFAGQLLANGHVGDALLGVGMEP-KEFVMLQPELW 454
            |:.|.|.:|                                  :|..|:.||. ::|:    |.|
 Frog   127 LQNHIDKFD----------------------------------EAEKGLLMEDVQKFL----EYW 153

  Fly   455 QKPRHLKRGQLHNLSHSDPITAIN-----------------LPYLSLCNHACEPSIRTKFDGCSV 502
              |...::..:..:||...:.:.|                 .|.|.|.||.|.|:       |:|
 Frog   154 --PSQSQQFGMQYISHIFSVISCNGFTLSDQRGLQAVGVGIFPNLCLANHDCWPN-------CTV 209

  Fly   503 V----NY----------------AAKDILEGEEIFNCYTMDYRNSLKLQRSHPLKAIYKFECTCA 547
            :    |:                |...|.:|||:...| :|:.| |...|...||..|.|:|||.
 Frog   210 IFNNGNHEAVRSMFHTQMRIELRALGKINKGEELTVSY-VDFLN-LTEDRKAQLKKQYYFDCTCE 272

  Fly   548 KCTRTDPD------------------QNYLSFHRYRCEK-PNCRQEFLPD--AKVQQNNLRWWLR 591
            .||:...|                  :..:.:.:...|| ...|.|.|.:  .|:.::.|:
 Frog   273 HCTKKTKDALLLAVKDGEDKPEERVVKEVIQYSKDTMEKIEKARSEGLYNDVVKLCRDCLK---- 333

  Fly   592 CNAEKPITC-TVCHELQHFAWYNE---FLGLIGSSADSSKRQALFKAFDDLDKWLVDHH 646
              .::||.. |..:.|:..:.|:|   :|.:...:|:::|:.        :|.:|..:|
 Frog   334 --RQEPIFADTNIYMLRILSIYSEVLSYLQMFDDAAENAKKM--------VDGYLKIYH 382

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Smyd4-1	NP_610500.2	SET	217..>252	CDD:394802	14/49 (29%)
		zf-MYND	258..298	CDD:460312	11/39 (28%)
		SET	<359..549	CDD:394802	46/227 (20%)
smyd1	XP_012811600.1	SET_SMYD1	2..276	CDD:380924	86/392 (22%)
		zf-MYND	47..85	CDD:460312	17/52 (33%)