Protein Alignment Nt5c and Nt5dc2

DIOPT Version :10

• Sequence 1: NP_610499.2
• Gene: Nt5c / 35984
• FlyBaseID: FBgn0033426
• Length: 548
• Species: Drosophila melanogaster
• Sequence 2: NP_001361016.1
• Gene: Nt5dc2 / 70021
• MGIID: 1917271
• Length: 553
• Species: Mus musculus
• Alignment Length: 563
• Identity: 243/563 - (43%)
• Similarity: 338/563 - (60%)
• Gaps: 56/563 - (9%)

  Fly     1 MCAAGSPIVSALLRQNVLLRAGGVLRSWDPISSSLSPS-----PCKPNYSFEARAFASDAGASAP 60
            |..||   :.|..|:.:|.|...     .|.::|.|||     |..|.      |.......|||
Mouse     1 MAGAG---LRATARRLLLCRGHS-----GPRAASSSPSCPGCGPPGPG------AHCPSTPRSAP 51

  Fly    61 AATAQISHP--KTVSDFQKL-HEATKKKFQSKKLPSDV----HPDAVFACNELDLSEVQVYGFDY 118
            |..|.:|..  ....|.::| |:.         ||.:|    :|.|::|.||:.||:|:||||||
Mouse    52 ADGADLSAHLWARYQDMRRLVHDL---------LPPEVCSLLNPAAIYANNEISLSDVEVYGFDY 107

  Fly   119 DYTLACYKPILEDLLYNLAREMLVKRFRYPEDILQLEYEPNFAVRGLHYDVEKGLLVKLDSFLQL 183
            |||||.|...|...::|.||::|::.::|||.|.:.:|:|:||:||||||::|.||:|:|:|..:
Mouse   108 DYTLAQYADALHPEIFNAARDILIEHYKYPEGIRKYDYDPSFAIRGLHYDIQKSLLMKIDAFHYV 172

  Fly   184 QLGSVYRGRTKVEADEVLKLY----HNRLLPIA--YVEGPNNSYRHNTNSKMVQLADLFSVPEMC 242
            |||:.|||...|..|||:.||    |..|..::  |.:||:          :.|..|:||:|||.
Mouse   173 QLGTAYRGLKPVPDDEVIDLYGGTQHIPLYQMSGFYGKGPS----------IKQFMDIFSLPEMA 227

  Fly   243 LLCNVIEYFERNRIDYNPEIVFHDTRTAMGSCH--PIMHGKVMRNTEKYIERNPKLVKFFEKLQQ 305
            ||..|::||..:.::::...::.|...|:...|  .:|:..:.::.||||.|..:......:|..
Mouse   228 LLSCVVDYFLGHGLEFDQVHLYKDVTDAIRDVHVKGLMYQWIEQDMEKYILRGDETFAVLSRLVA 292

  Fly   306 AGKNLFLVTNSPYSFVNCGMSFLVGANWRDFFDVVIVQARKPKFFTDESRPIRLFDERTQSHLWD 370
            .||.|||:||||:|||:.||..:||.:||..||||||||.||.||||..:|.|..||:...| ||
Mouse   293 HGKQLFLITNSPFSFVDKGMRHMVGPDWRQLFDVVIVQADKPNFFTDRRKPFRKLDEKGSLH-WD 356

  Fly   371 RVFKLEKGKIYYEGSVRQLQELKGWRGHSVLYFGDHPYSDLADVTLKHSWRTGAIISELAHEIKT 435
            |:.:|||||||.:|::.....|..|||..|||||||.||||||:.|:|.|||||||.||..||:.
Mouse   357 RITRLEKGKIYRQGNLFDFLRLTEWRGPRVLYFGDHLYSDLADLMLRHGWRTGAIIPELEREIRI 421

  Fly   436 LNRKDFKMSANWLQMLTQLIEDTQD-DDSEAAQICLKEWMEERDQLRNKTKNVFNEQFGSVFRTY 499
            :|.:.:..|..|.|.||.|:|..|. .|:|:.|: |..||:||.:||..||.:||.||||:|||:
Mouse   422 INTEQYMHSLTWQQALTGLLERMQTYQDAESRQV-LATWMKERQELRCITKALFNAQFGSIFRTF 485

  Fly   500 HNPTYFSRRLFRFADIYTSDITNLLKFSTTHTFYPRRGVMPHE 542
            ||||||||||.||:|:|.:.::.||.:....||||||..:.||
Mouse   486 HNPTYFSRRLVRFSDLYMASLSCLLNYRVDFTFYPRRTPLQHE 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nt5c	NP_610499.2	5_nucleotid	108..544	CDD:461733	211/444 (48%)
Nt5dc2	NP_001361016.1	5_nucleotid	97..530	CDD:461733	211/444 (48%)