Protein Alignment Alp6 and PHO8

DIOPT Version :10

• Sequence 1: NP_610496.1
• Gene: Alp6 / 35981
• FlyBaseID: FBgn0033423
• Length: 515
• Species: Drosophila melanogaster
• Sequence 2: NP_010769.3
• Gene: PHO8 / 852092
• SGDID: S000002889
• Length: 566
• Species: Saccharomyces cerevisiae
• Alignment Length: 572
• Identity: 152/572 - (26%)
• Similarity: 220/572 - (38%)
• Gaps: 174/572 - (30%)

  Fly    32 DAESHPIKYAEEQQTQYWVDKAQA----KLLSKLAEQES----ATTNKAKNVILFLGDGMSVHTV 88
            |:.|.|.|....::::..|.....    .:|.:||...|    :.::|.||||.|:.|||...::
Yeast    18 DSSSRPKKRRISKRSKIIVSTVVCIGLLLVLVQLAFPSSFALRSASHKKKNVIFFVTDGMGPASL 82

  Fly    89 TATRNLLGDSAEQVYFEGFP----------YTGLSKTYCVNRQVADSACTATAYLGGVKANYGTI 143
            :..|:.      ..:....|          :.|.|:|...:..|.|||..|||:...:|:..|.|
Yeast    83 SMARSF------NQHVNDLPIDDILTLDEHFIGSSRTRSSDSLVTDSAAGATAFACALKSYNGAI 141

  Fly   144 GVNANVSRYSCDGAANEEDRVLSIAHWAQAAGKDAGLVTTARVTHASPAGVYAHIADRNWENDWE 208
            ||:.:  ...|.          ::...|:.||...|||.|.|:|.|:||...:|: |..|:.|
Yeast   142 GVDPH--HRPCG----------TVLEAAKLAGYLTGLVVTTRITDATPASFSSHV-DYRWQED-- 191

  Fly   209 VANRECDPEQTIDIARQLVEQPVGQQLKVILGGGRKNFI-DATVNDEEGYPGKRTDGRHLIRSWL 272
                       :....||.|.|:|:.:.:::||||.:|. ........|:.|.|.|||.||
Yeast   192 -----------LIATHQLGEYPLGRVVDLLMGGGRSHFYPQGEKASPYGHHGARKDGRDLI---- 241

  Fly   273 DQKKEANVSAKYVWSRKGL-SLVDL--EN-TDYLLGLFANDHLPYNGDRDRKRSQLADPSLSELT 333
             .:.::| ..:||..||.. ||:..  || |...|||||::.:|:..|||.|..    |||.|..
Yeast   242 -DEAQSN-GWQYVGDRKNFDSLLKSHGENVTLPFLGLFADNDIPFEIDRDEKEY----PSLKEQV 300

  Fly   334 EAAITVL---SRNDK---GFFLFVEGARIDMAHHDTFAKRSLEDTAEFARAVQKAREL--TSEDD 390
            :.|:..|   |..||   ||||.|||:|||.|.|.......:.:...|..|.|...|.  .|:.:
Yeast   301 KVALGALEKASNEDKDSNGFFLMVEGSRIDHAGHQNDPASQVREVLAFDEAFQYVLEFAENSDTE 365

  Fly   391 TLIVVTADHAHVMSINGYPYRDQEITGLAQLADDNLPY-------TILSYANGPGYYSGYNRAEG 448
            |::|.|:||              |..||.........|       .:|:.|...|.:
Yeast   366 TVLVSTSDH--------------ETGGLVTSRQVTASYPQYVWYPQVLANATHSGEF-------- 408

  Fly   449 RALLKEKLV-------------------------------ADSDYQYPTLAPLDAE--------- 473
               ||.|||                               .|||.:  ||..||..
Yeast   409 ---LKRKLVDFVHEHKGASSKIENFIKHEILEKDLGIYDYTDSDLE--TLIHLDDNANAIQDKLN 468

  Fly   474 ------------THGGD--DVAVYASGPYA----------QYFSGNYEQSNI 501
                        |||..  ||.:||   ||          ....||:|.:.:
Yeast   469 DMVSFRAQIGWTTHGHSAVDVNIYA---YANKKATWSYVLNNLQGNHENTEV 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Alp6	NP_610496.1	alkPPc	73..512	CDD:214515	142/523 (27%)
PHO8	NP_010769.3	Alk_phosphatase	66..527	CDD:395188	142/524 (27%)