Protein Alignment Alp6 and Alpi

DIOPT Version :10

• Sequence 1: NP_610496.1
• Gene: Alp6 / 35981
• FlyBaseID: FBgn0033423
• Length: 515
• Species: Drosophila melanogaster
• Sequence 2: NP_001074551.1
• Gene: Alpi / 76768
• MGIID: 1924018
• Length: 554
• Species: Mus musculus
• Alignment Length: 535
• Identity: 223/535 - (41%)
• Similarity: 291/535 - (54%)
• Gaps: 73/535 - (13%)

  Fly     5 FILLLVLAVCLSGSASGQRDHPRGRSFDAESHPIKYAEEQQTQYWVDKAQAKLLSKLAEQESATT 69
            ::|||.|         |.|.|        .|..|..|||:...:|..|| |:.|....:.:...|
Mouse     5 WVLLLFL---------GLRIH--------LSFGIIPAEEENPAFWNKKA-AEALDAAKKLQPIQT 51

  Fly    70 NKAKNVILFLGDGMSVHTVTATRNLLGDSAEQVYFEG------------FPYTGLSKTYCVNRQV 122
            : |||:|:||||||.|.||||||.|.|.      .||            |||..|||||.|:|||
Mouse    52 S-AKNLIIFLGDGMGVPTVTATRILKGQ------LEGHLGPETPLAMDLFPYMALSKTYNVDRQV 109

  Fly   123 ADSACTATAYLGGVKANYGTIGVNANVSRYSCDGAANEEDRVLSIAHWAQAAGKDAGLVTTARVT 187
            .|||.||||||.||||||.|||::|......|:.....|  |.|:.:.|:.|||..|:|||.||.
Mouse   110 PDSAGTATAYLCGVKANYKTIGLSAAARLDQCNTTFGNE--VFSVMYRAKKAGKSVGVVTTTRVQ 172

  Fly   188 HASPAGVYAHIADRNWENDWEVANRECDPEQTI-----DIARQLVEQPVGQQLKVILGGGRKNFI 247
            ||||||.|||..:|||.:|.|:      |...:     |||.||:.   ...:.||||||||...
Mouse   173 HASPAGTYAHTVNRNWYSDAEM------PASALQDGCKDIATQLIS---NMDIDVILGGGRKFMF 228

  Fly   248 DATVNDEEGYP------GKRTDGRHLIRSWLDQKKEANVSAKYVWSRKGLSLVDLE-NTDYLLGL 305
            .....|.| ||      |.|.|.::|:::||.:.:    .|:|||:|..|.....: ...:|:||
Mouse   229 PKGTPDPE-YPSDSNQSGTRLDDQNLVQTWLSKHQ----GARYVWNRSELIQASQDPAVTHLMGL 288

  Fly   306 FANDHLPYNGDRDRKRSQLADPSLSELTEAAITVLSRNDKGFFLFVEGARIDMAHHDTFAKRSLE 370
            |....:.|    |..|:...||||:|:||.|:.:||||.:||:|||||.|||..||...|..:|.
Mouse   289 FEPTEMKY----DANRNPSVDPSLAEMTEVAVRMLSRNPQGFYLFVEGGRIDQGHHAGTAYLALT 349

  Fly   371 DTAEFARAVQKARELTSEDDTLIVVTADHAHVMSINGYPYRDQEITGLAQL-ADDNLPYTILSYA 434
            :...|..|::||.:||:|.||||::||||:||.:..||..|...|.|||.| |.|:..||.:.|.
Mouse   350 EAVMFDSAIEKASQLTNEKDTLILITADHSHVFAFGGYTLRGTSIFGLAPLKALDDKSYTSILYG 414

  Fly   435 NGPGYYSGYNRAEGRALLKEKLVADSDYQYPTLAPLDAETHGGDDVAVYASGPYAQYFSGNYEQS 499
            |||||..   ::..|..:.|....|.:|:.....||.:|||||:|||::|.||.|....|..||:
Mouse   415 NGPGYEL---KSGNRPNVTEAQSVDPNYKQQAAVPLSSETHGGEDVAIFARGPQAHLVHGVQEQN 476

  Fly   500 NIPALMARAAGIGPY 514
            .|..:||.|..:.||
Mouse   477 YIAHVMAFAGCLEPY 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Alp6	NP_610496.1	alkPPc	73..512	CDD:214515	202/463 (44%)
Alpi	NP_001074551.1	Alk_phosphatase	53..488	CDD:395188	203/463 (44%)