Protein Alignment Alp6 and Akp3

DIOPT Version :10

• Sequence 1: NP_610496.1
• Gene: Alp6 / 35981
• FlyBaseID: FBgn0033423
• Length: 515
• Species: Drosophila melanogaster
• Sequence 2: NP_073171.2
• Gene: Akp3 / 64621
• RGDID: 621650
• Length: 558
• Species: Rattus norvegicus
• Alignment Length: 503
• Identity: 220/503 - (43%)
• Similarity: 276/503 - (54%)
• Gaps: 67/503 - (13%)

  Fly    42 EEQQTQYWVDKAQAKLLSKLAEQESATTNKAKNVILFLGDGMSVHTVTATRNLLGDSAEQVYFEG 106
            ||:...:|..||...|  .:|::.......|||:|:||||||.|.||||||.|.|.      .||
  Rat    24 EEENPAFWNQKAADAL--NVAKKLQPIQTSAKNLIIFLGDGMGVPTVTATRILKGQ------LEG 80

  Fly   107 ------------FPYTGLSKTYCVNRQVADSACTATAYLGGVKANYGTIGVNANVSRYSCDGAAN 159
                        |||..|||||.|:|||.|||.||||||.|||.||.||||:|......|:....
  Rat    81 NLGPETPLAMDHFPYMALSKTYSVDRQVPDSASTATAYLCGVKTNYKTIGVSAAARFDQCNTTFG 145

  Fly   160 EEDRVLSIAHWAQAAGKDAGLVTTARVTHASPAGVYAHIADRNWENDWEVANRECDPEQTI---- 220
            .|  |||:.:.|:.|||..|:|||.||.||||||.|.|..:|||..|.::      |...:
  Rat   146 NE--VLSVMYRAKKAGKSVGVVTTTRVQHASPAGTYVHTVNRNWYGDADM------PASALQEGC 202

  Fly   221 -DIARQLVEQPVGQQLKVILGGGRKNFIDATVNDEEGYP------GKRTDGRHLIRSWLDQKKEA 278
             |||.|||.   ...:.||||||||....|...|.| ||      |.|.||::|::.||.:.:
  Rat   203 KDIATQLVS---NMDINVILGGGRKYMFPAGTPDPE-YPNDVNETGTRLDGKNLVQEWLSKHQ-- 261

  Fly   279 NVSAKYVWSRKGLSLVDLE-NTDYLLGLFANDHLPYNGDRDRKRSQLADPSLSELTEAAITVLSR 342
              .::|||:|:.|....|: :..||:|||.    |.:...:.:|..|.||||.::||||:.||||
  Rat   262 --GSQYVWNRQELIQKSLDPSVTYLMGLFE----PVDTKFEIQRDPLMDPSLKDMTEAALHVLSR 320

  Fly   343 NDKGFFLFVEGARIDMAHHDTFAKRSLEDTAEFARAVQKARELTSEDDTLIVVTADHAHVMSING 407
            |.|||:|||||.|||..||...|..:|.:...|..|:::|.:||||.|||.:|||||:||.|..|
  Rat   321 NPKGFYLFVEGGRIDRGHHLGTAYLALTEAVMFDSAIERASQLTSEQDTLTIVTADHSHVFSFGG 385

  Fly   408 YPYRDQEITGLAQL-ADDNLPYTILSYANGPGYYSGYNR-----AEGRALLKEKLVADSDYQYPT 466
            |..|...|.|||.| |.|..|||.:.|.|||||.....|     ||..         |..||...
  Rat   386 YTLRGTSIFGLAPLNALDGKPYTSILYGNGPGYVGTGERPNVTDAESH---------DPSYQQQA 441

  Fly   467 LAPLDAETHGGDDVAVYASGPYAQYFSGNYEQSNIPALMARAAGIGPY 514
            ..|:.:|||||:|||::|.||.|....|..||:.|..:||.|..:.||
  Rat   442 AVPVKSETHGGEDVAIFARGPQAHLLHGVQEQNYIAHVMAFAGCLEPY 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Alp6	NP_610496.1	alkPPc	73..512	CDD:214515	210/468 (45%)
Akp3	NP_073171.2	Alk_phosphatase	52..486	CDD:395188	211/468 (45%)