Protein Alignment Alp6 and alpi.2

DIOPT Version :9

• Sequence 1: NP_610496.1
• Gene: Alp6 / 35981
• FlyBaseID: FBgn0033423
• Length: 515
• Species: Drosophila melanogaster
• Sequence 2: NP_001020359.1
• Gene: alpi.2 / 574009
• ZFINID: ZDB-GENE-050626-142
• Length: 521
• Species: Danio rerio
• Alignment Length: 489
• Identity: 212/489 - (43%)
• Similarity: 281/489 - (57%)
• Gaps: 40/489 - (8%)

  Fly    42 EEQQTQYWVDKAQAKLLSKLAEQESATTNKAKNVILFLGDGMSVHTVTATRNLLGDSAEQ----- 101
            ||:...:|..||:..|.:.|:  .:..|::|||:||||||||.:.||||.|.|.|...::
Zfish    28 EEKNPNFWYVKAKDSLHASLS--MTFNTHRAKNLILFLGDGMGISTVTAARVLKGQMNKKTGEES 90

  Fly   102 -VYFEGFPYTGLSKTYCVNRQVADSACTATAYLGGVKANYGTIGVNANVSRYSCDGAANEEDRVL 165
             :..:.|||..|||||.|::|:.|||.||||||.||||||||:|::|...|..|......|  |.
Zfish    91 VLAMDTFPYLALSKTYNVDQQMPDSAATATAYLCGVKANYGTLGLSAAAQREVCSSVKGNE--VK 153

  Fly   166 SIAHWAQAAGKDAGLVTTARVTHASPAGVYAHIADRNWENDWEVANRE----CDPEQTIDIARQL 226
            ||.|.|:.|||..|:|:||||.|||||..|:|..:|.|.:|.|:.:..    |.     |||.||
Zfish   154 SILHQAKMAGKSVGIVSTARVQHASPAASYSHTPERGWYSDKELTSEAVAGGCQ-----DIAVQL 213

  Fly   227 VEQPVGQQLKVILGGGRKNFIDATVNDEE--GYPGKRTDGRHLIRSWLDQKKEANVSAKYVWSRK 289
            :   ....:.|||||||:........|.|  ...|.|.|.|:|:..||..:|    :|:|||:::
Zfish   214 I---TNTDINVILGGGRQYMFPRETTDPEYSTVTGSRKDKRNLVDEWLKNRK----NAQYVWNKQ 271

  Fly   290 GLSLVDLENTDYLLGLFANDHLPYNGDRDRKRSQLADPSLSELTEAAITVLSRNDKGFFLFVEGA 354
            ....|:.:.||||:|||......|..:||.|    .||||:|:.|.||.:|.:|..||:|||||.
Zfish   272 QFDAVNEDKTDYLMGLFEPKDTRYELERDPK----MDPSLTEMVEKAIKILRKNPNGFYLFVEGG 332

  Fly   355 RIDMAHHDTFAKRSLEDTAEFARAVQKARELTSEDDTLIVVTADHAHVMSINGYPYRDQEITGLA 419
            |||..||...||.:|.:..||..::::|.:||||.|||.||||||:||.|..||.||...:.|::
Zfish   333 RIDHGHHAGQAKYALTEAVEFDNSIERAGQLTSELDTLSVVTADHSHVFSFGGYSYRGNPVLGVS 397

  Fly   420 QL-ADDNLPYTILSYANGPGYY--SGYNRAEGRALLKEKLVADSDYQYPTLAPLDAETHGGDDVA 481
            .. .:|...:|...|.|||||.  :|     .|..:.|.:....||......|||:||||.:|||
Zfish   398 YAKGEDGKSFTNALYGNGPGYQITNG-----TRPDVNESVSGRDDYLQQAAVPLDSETHGSEDVA 457

  Fly   482 VYASGPYAQYFSGNYEQSNIPALMARAAGIGPYA 515
            ::|.||.|..|.|..|||.||..||.||.|.||:
Zfish   458 IFAKGPMAHLFHGVQEQSYIPHAMAFAACIEPYS 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Alp6	NP_610496.1	ALP_like	72..511	CDD:304875	201/453 (44%)
alpi.2	NP_001020359.1	Alk_phosphatase	56..487	CDD:278666	201/453 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170593251
Domainoid	1	1.000	363	1.000	Domainoid score	I896
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	383	1.000	Inparanoid score	I2001
OMA	1	1.010	-	-		QHG48882
OrthoDB	1	1.010	-	-		D216917at33208
OrthoFinder	1	1.000	-	-		FOG0000192
OrthoInspector	1	1.000	-	-		mtm6481
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11596
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X159
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	12	12.010