Protein Alignment Alp6 and alpl

DIOPT Version :9

• Sequence 1: NP_610496.1
• Gene: Alp6 / 35981
• FlyBaseID: FBgn0033423
• Length: 515
• Species: Drosophila melanogaster
• Sequence 2: NP_957301.2
• Gene: alpl / 393982
• ZFINID: ZDB-GENE-040420-1
• Length: 561
• Species: Danio rerio
• Alignment Length: 536
• Identity: 229/536 - (42%)
• Similarity: 295/536 - (55%)
• Gaps: 71/536 - (13%)

  Fly     4 RFILLLVLAVCLSGSASGQRDHPRGRSFDAESHPIKYAEEQQTQYWVDKAQAKLLSKLAEQESAT 68
            :.:.||:|: ||......:...|.              :|::..||.|.||..|...|..|| ..
Zfish    36 KVVQLLILS-CLVWEGKTKVQFPE--------------QEKRPDYWRDFAQRSLKDALKLQE-LN 84

  Fly    69 TNKAKNVILFLGDGMSVHTVTATR----NLLGDSAE--QVYFEGFPYTGLSKTYCVNRQVADSAC 127
            .|.|||:||||||||.|.||||.|    .|.|.:.|  |:..:.||:..|||||..|.||.|||.
Zfish    85 KNIAKNIILFLGDGMGVPTVTAARILKGQLSGQNGEETQLEMDKFPHVALSKTYNTNAQVPDSAG 149

  Fly   128 TATAYLGGVKANYGTIGVNANVSRYSCDGAANEEDRVLSIAHWAQAAGKDAGLVTTARVTHASPA 192
            ||||:|.|||||.||:||:|...|..|:.....|  |.||..||:.|||..|:|||.||.||:|:
Zfish   150 TATAFLCGVKANEGTVGVSAAAVRSQCNTTQGNE--VTSILKWAKDAGKSVGIVTTTRVNHATPS 212

  Fly   193 GVYAHIADRNWENDWEVANRECDPEQTIDIARQLVEQ-PVGQQLKVILGGGRKNFIDATVNDEEG 256
            ..|||..||:|.:|.::.| |.......||||||.|. |   .:.||:||||::.......|.|
Zfish   213 AAYAHCVDRDWYSDADMPN-EALQSGCKDIARQLFENIP---DINVIMGGGRRSMYPKNTPDVE- 272

  Fly   257 YP------GKRTDGRHLIRSWLDQKKEANVSAKYVWSRKGLSLVDLENTDYLLGLFANDHLPYNG 315
            ||      |.|.|||:|:..|:|:.||..  ..|||::|.|..::..|.|||||||....|.|..
Zfish   273 YPGDKKQNGTRKDGRNLVGEWIDRVKEKR--GFYVWNKKDLLSLNPNNVDYLLGLFEPADLNYEL 335

  Fly   316 DRDRKRSQLADPSLSELTEAAITVLSRNDKGFFLFVEGARIDMAHHDTFAKRSLEDTAEFARAVQ 380
            :|:.:.    ||||:|:.:.||.:|.:|::||||.|||.|||..||:..||::|.:..|..||:.
Zfish   336 ERNTEN----DPSLTEMVDVAIKILKKNERGFFLLVEGGRIDHGHHEGKAKQALHEAVEMDRAIT 396

  Fly   381 KARELTSEDDTLIVVTADHAHVMSINGYPYRDQEITGLA-QLAD-DNLPYTILSYANGPGYYSGY 443
            :|..||||.|||.||||||:||.|..||..|...|.||| .|:| |..|:|.:.|.||||:
Zfish   397 RAGLLTSEYDTLTVVTADHSHVFSFGGYTPRGNSIFGLAPTLSDVDQKPFTAILYGNGPGF---- 457

  Fly   444 NRAEGRALLKEKLV------------ADSDYQYPTLAPLDAETHGGDDVAVYASGPYAQYFSGNY 496
                       |||            ..::||..:..||..|||||:|||:::.||.|....|..
Zfish   458 -----------KLVNGARENVSTVDYQQNNYQAQSAVPLRMETHGGEDVAIFSKGPMAHLLHGVQ 511

  Fly   497 EQSNIPALMARAAGIG 512
            ||..||.:||.||.||
Zfish   512 EQHYIPHVMAYAACIG 527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Alp6	NP_610496.1	ALP_like	72..511	CDD:304875	210/465 (45%)
alpl	NP_957301.2	Alk_phosphatase	88..526	CDD:278666	210/465 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170593264
Domainoid	1	1.000	363	1.000	Domainoid score	I896
eggNOG	1	0.900	-	-		E1_COG1785
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	383	1.000	Inparanoid score	I2001
OMA	1	1.010	-	-		QHG48882
OrthoDB	1	1.010	-	-		D216917at33208
OrthoFinder	1	1.000	-	-		FOG0000192
OrthoInspector	1	1.000	-	-		mtm6481
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11596
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X159
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	13	12.910